The Prevalence of dysglycaemia and other cardiovascular risk factors among first degree relatives of Irish patients with type 2 diabetes in Ireland

Abstract

Objectives: To assess the prevalence of diabetes, pre-diabetes and other cardiovascular risk factors amongst close relatives of patients with type2 diabetes. Methods: 100 participants aged between 25 and 75 years were recruited through their first degree relatives, who have type 2diabetes and attend Naas Hospital diabetes clinic. Participants underwent an oral glucose tolerance test, cardiovascular risk factor assessment and completed a questionnaire. Results: 60% of participants were females with a mean age of 45.9 years, 95% CI (44.08-47.8). 21% had dysglycaemia (One with diabetes and 20 pre-diabetes). 34% had un-diagnosed hypertension and 8% were known hypertensive but not controlled. 71% had dyslipidaemia.23% were overweight, while 38% were obese. Fasting blood glucose correlated positively with age (p=0.047), BMI (p=0.02), systolic BP (p=0.003) and triglycerides levels (p=0.023). Conclusion: First degree relatives of type 2 diabetes patients showed relatively low prevalence of dysglycaemia, but a high prevalence of dyslipidaemia, hypertension and obesity.