The prevalence of essential tremor in Edirne and its counties accompanied comorbid conditions

Güler, Sibel; Çaylan, Ayşe; Turan, Fatma Nesrin; Dağdeviren, Nezih

doi:10.1080/01616412.2019.1628409

Cited by 8 publications

(9 citation statements)

References 27 publications

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“…In the 14 more recent studies, methodologies have advanced, and isolated head tremor was specifically noted to be present or absent in 7 of these studies. In these seven studies, the prevalence of isolated head tremor was as follows: 0.0% [47,48,55,57], 0.6% [56], 1.6% [49], 4.6% [51]. Overall, from the studies reviewed in our 2010 paper and from the more recent studies, the bulk of evidence indicates that the prevalence of isolated head tremor likely ranges between 0% and 5%.…”

Section: Isolated Head Tremormentioning

confidence: 70%

“…While most prevalence studies reported in our 2010 paper defined ET, we reported that six did not [14]. In the 14 studies that have been published since that report, all have provided explicit definitions of ET [20,[45][46][47][48][49][50][51][52][53][54][55][56][57], which represents an improvement in methodology over time. However, we had noted in the earlier report that the large majority of studies used definitions that either did not specify the examination that was performed on participants or the minimal severity of tremor that was required to qualify for a diagnosis [14].…”

Section: Descriptive Analytic Approach Pertinent Methodological Issues That Arise When Interpreting Data From Prevalence Studiesmentioning

confidence: 99%

“…Furthermore, for those studies reporting prevalence beginning at halfdecades (e.g., 55-64), the numerical value was recorded as the average of the two decades. Lastly, those studies reporting data that completely spanned two decades, other than those in the 0-39 strata, were excluded (e.g., [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59]. Based on the results of this analysis, it is estimated that the prevalence increases by a factor of 1.74, or 74%, for every decade increase in age (p < 0.0001).…”

Section: Meta-analysismentioning

confidence: 99%

“…Numerous studies provided data on the percentage of identified cases who were undiagnosed prior to the prevalence survey. These percentages are as follows: 100% (Tanzania) [25], 97.2% (Nigeria) [47], 97.1% (Finland) [11], 96.3% (Faroe Islands) [55], 92.8% (Turkey) [38], 92.2% (Turkey) [49], 91.0% (Turkey, Brazil) [10,50], 90.0% (Singapore) [29], 87.7% (Spain) [51], 79.7% (Spain) [40], 78.9% (USA) [54], and 59.5% (Turkey) [56]. These countries, which represent a broad socioeconomic range, indicate that the large bulk of population-dwelling ET cases are not seeking medical attention for their tremor and remain undiagnosed at the time of prevalence surveys.…”

Section: Previously Undiagnosed Etmentioning

confidence: 99%

“…In addition, the 2010 review did not capture one paper [21]. Hence, this review includes 27 studies [10][11][12][13] that were covered in the prior review, one that was not captured in the prior review [21], and 14 new ones [20,[45][46][47][48][49][50][51][52][53][54][55][56][57] for a total of 42 [10-13, 20, 22-57]. These 42 studies were from 23 countries across 6 continents (Asia = 18, Europe = 10, North America = 6, Africa = 5, South America = 2, Australian continent = 1) [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

How Common is Essential Tremor? Update on the Worldwide Prevalence of Essential Tremor

Louis

McCreary

2021

Tremor and Other Hyperkinetic Movements

127

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Background: Essential tremor (ET) is among the most prevalent movement disorders. Comprehensive reviews of disease prevalence were published in 1998 and 2010 but not since then. We reviewed the prevalence of ET in population-based epidemiological studies, derived a precise summary estimate of prevalence from these studies, and examined differences in prevalence across studies. We used two methods: a descriptive-analytical approach and a meta-analysis.Methods: A PUBMED search yielded 14 published papers since the 2010 review.Results: There were 42 population-based prevalence studies (23 countries and 6 continents). In a meta-analysis, pooled prevalence (all ages) = 1.33%, with statistically significant heterogeneity across studies (I 2 = 99.3%, p < 0.0001). In additional descriptive analyses, median crude prevalence (all ages) = 0.4% and mean = 0.67%. Prevalence increased markedly with age, and especially with advanced age. In the meta-analysis, prevalence (age ≥ 65 years) = 5.79%, and in descriptive analyses, median crude prevalence (age ≥ 60-65) = 5.9% and mean = 8.0%. In the oldest age groups, median prevalence = 9.3%, with several studies reporting values >20%. The prevalence increased by 74% for every decade increase in age (p < 0.0001). Gender did not impact the prevalence of ET (p = 0.90).Discussion: Precise prevalence estimates are important because they form the numerical basis for public health initiatives and offer clues about underlying biological factors of mechanistic importance. The prevalence of ET among those age ≥ 65 is similar to that reported for Alzheimer's disease in elders, suggesting that ET may be the most common neurodegenerative disease.

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Section: Isolated Head Tremormentioning

confidence: 70%

Section: Descriptive Analytic Approach Pertinent Methodological Issues That Arise When Interpreting Data From Prevalence Studiesmentioning

confidence: 99%

Section: Meta-analysismentioning

confidence: 99%

Section: Previously Undiagnosed Etmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

How Common is Essential Tremor? Update on the Worldwide Prevalence of Essential Tremor

Louis

McCreary

2021

Tremor and Other Hyperkinetic Movements

127

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Archimedes Spiral Ratings: Determinants and Population‐Based Limits of Normal

Hopfner,

Tietz,

D'Elia

et al. 2024

Movement Disord Clin Pract

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BackgroundTremor is commonly found among healthy humans or prevalently a symptom of neurological dysfunctions. However, the distinction between physiological and pathological tremor is dependent on the examiner's competence. Archimedes Spiral Rating (ASR) is a valid and reproducible semi‐quantitative method to assess the severity of action tremor.Objectives(1) To assess the range and percentiles of ASR in a large sample seemingly free of tremor‐related conditions or symptoms from the population‐based CHRIS‐study. (2) To analyze the influence of sex, age, and the drawing hand on ASR. (3) To define ASR limits of normal. (4) To supply exemplary Archimedes spiral drawings by each rating to favor consistent and proficient clinical evaluation.MethodsAccurately investigated participants were randomly sampled over 14 sex‐age strata. 2686 paired spirals drawn with both hands by 1343 participants were expertly assessed on a tremor rating scale from 0 to 9.ResultsASR had a quadratic increase with age in both sexes, while it was relatively lower in the dominant compared to the non‐dominant hand and in women compared to men. ASRs above sex‐age specific 97.5th percentiles of 4 and 5, below and above 60 years of age, respectively, were conceivably of non‐physiological nature.ConclusionsIn a large population‐based sample we show a steeper increase of action tremor by age as age progresses. Relatively higher ratings among the elderly, males and the non‐dominant hands, appear compatible with ASR limits of “normal” across sex‐age groups. The current operational evidence may support practitioners differentiating physiological and pathological hand tremor.

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Essential Tremor and Other Forms of Kinetic Tremor

Louis

2023

Contemporary Clinical Neuroscience

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The prevalence of essential tremor in Edirne and its counties accompanied comorbid conditions

Cited by 8 publications

References 27 publications

How Common is Essential Tremor? Update on the Worldwide Prevalence of Essential Tremor

How Common is Essential Tremor? Update on the Worldwide Prevalence of Essential Tremor

Archimedes Spiral Ratings: Determinants and Population‐Based Limits of Normal

Essential Tremor and Other Forms of Kinetic Tremor

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