The prevalence of Hepatitis B surface antigen and antibody in home-reared individuals with down syndrome

Pueschel, Siegfried M.; Bodenheimer, Henry C.; Giesswein, Peter; Dean, MT

doi:10.1016/0891-4222(91)90010-p

Cited by 6 publications

(7 citation statements)

References 25 publications

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“…That epilepsy might be a complication of Alzheimer's dementia in persons with Down's syndrome is suggested by the results of Lai & Williams (1989), Pueschel et al (1991), Collacott (1993), McVicker et al (1994 and Van Schrojenstein Lantman et al (1995).…”

Section: Discussionmentioning

confidence: 96%

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Comorbidity in people with Down's syndrome: a criteria‐based analysis

Valk¹,

Haveman

Crebolder

1996

J intellect Disabil Res

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The aims of this study were to review what is currently known about comorbidity in people with Down's syndrome and to determine if their relative risk for certain disorders was increased. Analysis was carried out on the published literature from 1982 through 1994. In order to be included in this study, articles had to meet predetermined criteria. The strengths and weaknesses of the selected articles were considered in this review. The estimation of relative risks was done by calculating the odds ratio (OR). Odds ratios of > 2 or < 0.5 were found in more than one article for congenital heart defects, hypothyroidism, hearing impairment and hepatitis B. Only one article indicated an OR within this range for all of the following disorders: obesity, epilepsy, degenerative spine disorders and a wide atlanto-axial distance. The results were unclear in the areas of hyperthyroidism, visual disorders, dementia and psychiatric disorders. The concept of comorbidity, i.e. establishing the relationships between the various conditions in one person and understanding the implications for medical care, seems promising, especially for people with intellectual disability. Further work in this area may well improve the quality of care offered to these people.

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Section: Discussionmentioning

confidence: 96%

“…For non-institutionalized people, the OR varied from 0.9-5.0. Only Pueschel et al (1991) gave results that indicate an OR<I, but the 95% confidence interval is broad (0.1-6.2). Most authors compared results from subjects with Down's syndrome to people with other forms of intellectual disability.…”

Section: Hepatitismentioning

confidence: 99%

Comorbidity in people with Down's syndrome: a criteria‐based analysis

Valk¹,

Haveman

Crebolder

1996

J intellect Disabil Res

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“…Non‐institutionalized people with DS are at no higher risk for HBV than the general population ( Boughton et al . 1976 ; Pueschel et al . 1991 ; Di Ciommo et al .…”

Section: Hepatitis Bmentioning

confidence: 99%

Hepatitis B and C in institutions for individuals with intellectual disability

Vellinga

Damme

Meheus

1999

J intellect Disabil Res

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People with intellectual disability are a well-known highrisk group for hepatitis B virus (HBV) infection. Hepatitis B virus is a major public health problem, but it is often neglected because of its largely asymptomatic course with long-term complications. Safe and effective vaccines have been available for over 15 years. However, universal vaccination strategies have not or have not completely been implemented to date, even though epidemiological data have indicated the effectiveness and efficacy of vaccination, and economic evaluations have shown that it is cost effective. Hepatitis C virus (HCV), which was discovered in 1989, has similar risk factors and is also a cause of chronic hepatitis. The prevalence of HCV amongst individuals with intellectual disability has not been clearly established. An overview of the literature on the prevalence of HBV and HCV in this population, as well as risk factors, transmission and prevention is presented in the present review. The literature cited in the present article was obtained by searches in MedLine using the following keywords and keyword combinations: hepatitis, hepatitis B virus, hepatitis C virus, mentally retarded, mentally handicapped, developmentally retarded, intellectual disability, institutionalization, Down's syndrome and hepatitis B vaccination. The search was done from 1980 to 1998. Beside this, the older articles found in the references were included if these were considered necessary for completeness.

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“…In contrast, persons with ID in community placements have a lower seroprevalence of hepatitis B (9.3-11%) [Devesa et al, 1993;Devlin et al, 1993] than those in institutions, especially children, in whom the incidence is estimated between 4 and 19.4% [Ellis et al, 1990;Garcia et al, 1990;Di Ciommo et al, 1993]. In addition, Pueschel et al [1991] found no significant differences in hepatitis B prevalence between people with Down syndrome living in the community and a general population control group.…”

Section: Sexually Transmitted Diseasesmentioning

confidence: 99%

Sexual health care in persons with intellectual disabilities

Servais

2006

Ment. Retard. Dev. Disabil. Res. Rev.

144

121

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In the past, preventive health concerning sexuality of people with intellectual disabilities was addressed through surgical sterilization as part of nationwide eugenic programs in many countries. For more than 30 years now, it has come progressively to light in the scientific literature that, besides major ethical and legal problems, these programs also failed to assess many of the individual's needs in sexual health. The fact that an increasing number of people with intellectual disabilities live in the community rather than in institutions has heightened public awareness that these individuals have sexual expectancies, desires, and needs that must be supported through both education and health services. The emergence of AIDS, including descriptions of cases among people with intellectual disabilities, has further demonstrated that surgical sterilization cannot be considered a global option to achieve preventive sexual health. The aim of this paper is to review scientific studies that have assessed the expectancies and support needs of persons with intellectual disabilities in terms of sexual health. These needs vary widely from one individual to another, according to life milieu, level of disability, and potential comorbidity. From this review, it appears that hygiene management, global gynecological care, and prevention of unplanned pregnancy, sexually transmitted diseases, and abuse have been frequently identified as areas in which the presence of intellectual disability dictates specific support needs. Different approaches that have been evaluated to address these issues will also be discussed. Key Words: sexuality; contraception; sterilization; sexually transmitted disease; hygiene management; pregnancy S exual health is influenced by a variety of political and social events and is broader than the absence of disease [Edwards and Coleman, 2004], encompassing both mental and physical aspects of human functioning that are important to overall well being [Sandfort and Ehrhardt, 2004]. The concept of sexual health in persons with intellectual disabilities (ID) is an extremely sensitive subject, and while advances have been made in employment, housing, and other aspects of community integration, the sexual needs of these individuals have been relatively ignored or strictly controlled by caregivers and service agencies [Bambara and Brantlinger, 2002; Hinsburger and Tough, 2002]. The importance of sexual health for people with ID has received increased attention in the past several decades and was recently highlighted by the 58th World Health Assembly (World Health Organization [(WHO)], which urged member states to include a disability component, including those with ID, in sexual health policies and programs [WHO, 2005a].Despite the heightened awareness of sexual health needs in this population, there has been a tendency to focus on issues of sexual rights and sexuality, and there is relatively less information on related factors such as preventive health. The U.S. Department of Health and Human Services (USDHHS...

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The prevalence of Hepatitis B surface antigen and antibody in home-reared individuals with down syndrome

Cited by 6 publications

References 25 publications

Comorbidity in people with Down's syndrome: a criteria‐based analysis

Comorbidity in people with Down's syndrome: a criteria‐based analysis

Hepatitis B and C in institutions for individuals with intellectual disability

Sexual health care in persons with intellectual disabilities

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