The prevalence of hip osteoarthritis: a systematic review and meta-analysis

Abstract

Objective To estimate the global prevalence of hip osteoarthritis (HOA) through a systematic review and meta-analysis, and to determine by regression analysis the respective relationships between age and sex, and sex and prevalence. Methods EMBASE, PubMed, Web of science, CINAHL, and SCOPUS were searched from inception until August 2022. Two authors independently extracted data and assessed the quality of the retrieved literature. Random-effects meta-analysis was performed to derive the pooled prevalence. Variations in the prevalence estimate in different subgroups, including diagnostic methods, region, and patient sex, were examined by subgroup meta-analysis. Meta-regression was used to construct the age-specific prevalence of HOA. Results A total of 31 studies were included in our analysis, involving 326,463 participants. Quality evaluation showed that all studies included in the analysis had a Quality Score of at least 4. The most frequently used method for diagnosing HOA was the Kellgren–Lawrence (K-L) grade classification, accounting for 19/31 (61.3%) studies. The pooled prevalence of HOA diagnosed based on the K-L grade ≥ 2 criterion was 8.55% (95% CI 4.85–13.18) worldwide. The prevalence of HOA was lowest in Africa at 1.20% (95% CI: 0.40–2.38), followed by Asia at 4.26% (95% CI 0.02–14.93) and North America at 7.95% (95% CI 1.98–17.36), and highest in Europe at 12.59% (95% CI 7.17–19.25). There was no statistically significant difference in HOA prevalence between men (9.42%, 95% CI:4.81–15.34) and women at (7.94%, 95% CI: 3.57–13.81). The regression model showed a correlation between age and the prevalence of HOA. Conclusion HOA has high prevalence worldwide and increases with age. The prevalence varies significantly by region but not by patient sex. High-quality epidemiological studies are warranted to more accurately estimate the prevalence of HOA.

Annual epidemiological and health insurance disease burden of hip osteoarthritis in Hungary based on nationwide data

“…In addition to age and sex, ethnicity and geographical region also determines the prevalence of hip osteoarthritis. Many studies showed that Europe (12.59%) and North America (7.95%) had a higher prevalence of hip OA compared to Asia (4.26%) and Africa (1.2%) [ 2 , 10 – 12 , 42 , 45 ].…”

Osteoporosis, Osteoarthritis, and Subchondral Insufficiency Fracture: Recent Insights

“…In the Framingham Study Community cohort, the age-standardized prevalence of radiographic HOA was 19.6%, and that of symptomatic HOA was 4.2% in individuals aged ≥ 50 [28]. In a recent meta-analysis, there were regional differences in the prevalence of HOA; the lowest was in Africa at 1.20%, followed by Asia at 4.26% and North America at 7.95%, and the highest was in Europe at 12.59%, but these did not vary by sex [29]. In a large-scale population of a nationwide cohort study, Research on Osteoarthritis/osteoporosis Against Disability in Japan, the incidence rate of radiographic HOA was 5.6/1000 person years and 8.4/1000 person years, and the progression rate was 2.2/1000 person years and 6.0/1000 person years in men and women, respectively [30].…”

Changing Stimulation Frequency Improves Implanted Peripheral Nerve Stimulator Effects Following Post-Traumatic Total Hip Arthroplasty: A Case Report

“…H ip osteoarthritis (OA) is characterized by the degeneration of articular cartilage and surrounding structures that clinically manifests with joint stiffness, groin pain, and reduced function. 1,2 With an overall prevalence of 10.9%, the hip is the second most commonly affected joint. 2 Pain and stiffness are often severe and progress over the years, threatening physical independence in the elderly.…”

“…While certain risk factors are found in young patients, aging is the principal etiological risk factor for hip OA. 1 Nonoperative management for hip OA include physical therapy, exercise, activity modifications, walking aids, and medication. Pharmaceutical management with oral Nonsteroidal-anti-inflammatory-drug (NSAIDs) are strongly recommended, as they are the mainstay for symptom relief of osteoarthritis.…”

“…Pain and stiffness are often severe and progress over the years, threatening physical independence in the elderly. While certain risk factors are found in young patients, aging is the principal etiological risk factor for hip OA 1 . Nonoperative management for hip OA include physical therapy, exercise, activity modifications, walking aids, and medication.…”