The prevalence of HIV infection among burn patients in a burns unit in Malawi and its influence on outcome

James, J; Hofland, Helma W. C.; Borgstein, Eric; Kumiponjera, Devor; Komolafe, OO; Zijlstra, Eduard E.

doi:10.1016/s0305-4179(02)00236-x

Cited by 26 publications

(38 citation statements)

References 9 publications

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“…Our figures for HIV infection among paediatric burn injury patients (2.3%) in the present study was found to be significantly low than that reported in Malawi (5.8%) at the same age group reflecting differences in the overall prevalence of HIV infection in general population from one country to another [35]. HIV infection in children in these studies is most likely to be caused by vertical transmission or by blood transfusion for malaria-related anemia.…”

Section: Discussioncontrasting

confidence: 70%

Pattern of childhood burn injuries and their management outcome at Bugando Medical Centre in Northwestern Tanzania

et al. 2011

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BackgroundBurn injuries constitute a major public health problem and are the leading cause of childhood morbidity and mortality worldwide. There is paucity of published data on childhood burn injuries in Tanzania, particularly the study area. This study was conducted to describe the pattern of childhood burn injuries in our local setting and to evaluate their management outcome.Methods A cross sectional study was conducted at Bugando Medical Centre (in Northwestern Tanzania) over a 3-year period from January 2008 to December 2010. Data was collected using a pre-tested coded questionnaire and statistical analyses performed using SPSS software version 15.0.ResultsA total of 342 burned children were studied. Males were mainly affected. Children aged = 2 were the majority accounting for 45.9% of cases. Intentional burn injuries due to child abuse were reported in 2.9% of cases. Scald was the most common type of burns (56.1%). The trunk was the most commonly involved body region (57.3%). Majority of patients (48.0%) sustained superficial burns. Eight (2.3%) patients were HIV positive. Most patients (89.8%) presented to the hospital later than 24 h. The rate of burn wound infection on admission and on 10th day were 32.4% and 39.8% respectively.Staphylococcus aureus were more common on admission wound swabs, with Pseudomonas aeruginosa becoming more evident after 10th day. MRSA was detected in 19.2% of Staphylococcus aureus. Conservative treatment was performed in 87.1% of cases. Surgical treatment mainly skin grafting (65.9%) was performed in 44 (12.9%) of patients. The overall average of the length of hospital stay (LOS) was 22.12 ± 16.62 days. Mortality rate was 11.7%. Using multivariate logistic regression analysis; age of the patient, type of burn, delayed presentation, clothing ignition, %TBSA and severity of burn were found to be significantly associated with LOS (P < 0.001), whereas mortality rate was found to be independently and significantly related to the age of the patient, type of burn, HIV positive with stigmata of AIDS, CD4 count, inhalation injury, %TBSA and severity of burn (P < 0.001).ConclusionChildhood burn injuries still remain a menace in our environment with virtually unacceptable high morbidity and mortality. There is need for critical appraisal of the preventive measures and management principles currently being practiced.

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Section: Discussioncontrasting

confidence: 70%

Pattern of childhood burn injuries and their management outcome at Bugando Medical Centre in Northwestern Tanzania

et al. 2011

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“…The overall mortality rate for burns admissions was 27%, which is higher than the reported mortality rates for burns patients (16.9 – 19.3%) from Queen Elizabeth Central Hospital in Blantyre, Malawi. 8,14 This difference in mortality rate between the hospitals may be explained by the fact that Blantyre has a dedicated burns unit with better infrastructure and staffing. The lower mortality rate at Blantyre is a goal to strive for as care improvement efforts at KCH are implemented.…”

Section: Discussionmentioning

confidence: 99%

The Epidemiology, Management, Outcomes and Areas for Improvement of Burn Care in Central Malawi: An Observational Study

Samuel

Campbell²,

Mjuweni

et al. 2011

J Int Med Res

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This report describes the epidemiology of burn injuries and quantifies the appropriateness of use of available interventions at Kamuzu Central Hospital, Malawi, between July 2008 and June 2009 (370 burn patients). Burns accounted for 4.4% of all injuries and 25.9% of all burns presenting to the hospital were admitted. Most patients (67.6%) were < 15 years old and 56.2% were male. The most frequent cause was scalding (51.4%). Burns occurred most frequently in the cool, dry season and in the evening. The mean burn surface area (second/third degree) was 14.1% and most burns (74%) presented within 8 h. The commonest procedure was debridement and/or amputation. The mean hospital stay was 21.1 days, in-hospital mortality was 27% and wound infection rate was 31%. Available interventions (intravenous fluids, nutrition therapy, physiotherapy) were misapplied in 59% of cases. It is concluded that primary prevention should address paediatric and scald burns, and secondary prevention should train providers to use available interventions appropriately.

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“…Burns are another common cause of injury, particularly in children (56). Burns Ͼ30% of the body surface area have been associated with excessively high mortality rate in Malawi (85).…”

Section: Supporting Disciplinesmentioning

confidence: 99%

A review and analysis of intensive care medicine in the least developed countries*

Dünser

Baelani

Lundeg

2006

Critical Care Medicine

222

200

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The prevalence of HIV infection among burn patients in a burns unit in Malawi and its influence on outcome

Cited by 26 publications

References 9 publications

Pattern of childhood burn injuries and their management outcome at Bugando Medical Centre in Northwestern Tanzania

Pattern of childhood burn injuries and their management outcome at Bugando Medical Centre in Northwestern Tanzania

The Epidemiology, Management, Outcomes and Areas for Improvement of Burn Care in Central Malawi: An Observational Study

A review and analysis of intensive care medicine in the least developed countries*

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