The Prevalence of <i>Helicobacter pylori</i> Antibody in Different Age Groups in Central Texas

Patterson, Tom; Straten, Emma; Jimenez, Stephanie

doi:10.29074/ascls.25.2.102

Cited by 15 publications

(14 citation statements)

References 10 publications

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“…In an existing cohort of Hispanic and NHW men, an overall H. pylori infection rate of 20% was identified, which was consistent with recent regional findings ( Patterson, Straten, & Jimenez, 2012 ). Sonnenberg et al (2010) reported that gastric biopsies from Texas residents had an overall infection rate of 12.7%.…”

Section: Discussionsupporting

confidence: 89%

“… Sonnenberg et al (2010) reported that gastric biopsies from Texas residents had an overall infection rate of 12.7%. A study done in central Texas reported a prevalence of 24% in persons aged 41 to 60 years compared with other age groups ( Patterson et al, 2012 ), but results were not stratified by ethnicity. As expected, the infection rate among Hispanics was much higher than NHWs (30% vs. 9%), consistent with previous reports of national data ( Grad et al, 2012 ).…”

Section: Discussionmentioning

confidence: 97%

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Helicobacter Pylori Infection in Texas Hispanic and Non-Hispanic White Men: Implications for Gastric Cancer Risk Disparities

et al. 2017

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Chronic Helicobacter pylori (H. pylori) infection is a major gastric adenocarcinoma (GA) risk factor. GA disproportionately affects U.S. Hispanics compared with non-Hispanic Whites (NHWs). Since H. pylori infection studies in Hispanics are few, infection rates in Hispanic and NHW men in Bexar County were compared, and relationships with ethnicity and obesity examined. Age- and zip code-matched participants from a community-dwelling cohort were randomly selected. Sera from 284 men were analyzed by enzyme immunoassay for H. pylori antibodies. Adjusted risk ratio estimation for matched data was conducted to identify differences. Hispanics had a markedly higher prevalence of infection (30.3%) than NHWs (9.2%). Matched risk ratio (mRR) analyses revealed a strong association between H. pylori seropositivity and Hispanic ethnicity (mRR = 3.31; 95% CI [1.91, 5.73], adjusted by BMI, smoking status, and family history of cancer (mRR range = 3.28–3.89). BMI mRRs (range = 1.19–1.22) were significant in all models. In this cohort, Hispanic men had higher H. pylori infection rates than NHWs, and parallel the disproportionately higher rates of GA; obesity contributes to this higher prevalence. Future studies should address country of origin, acculturation, and other factors influencing obesity to further elucidate risk of GA in Hispanic populations.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 97%

Helicobacter Pylori Infection in Texas Hispanic and Non-Hispanic White Men: Implications for Gastric Cancer Risk Disparities

et al. 2017

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“…Remarkably, analysis of waste pickers socio-demographic characteristics showed that seroprevalence of H. pylori was not only high among the youngest participants but also did not show a statistically significant increase with age. The former suggests an early exposure to H. pylori in waste pickers, and the latter is not consistent with the typical increase in the frequency of infection with age that has been reported in several studies [ 5 , 9 , 14 - 16 ]. Other putative socio-demographic factors associated with H. pylori infection, including low socioeconomic status [ 5 , 13 ] and low educational level [ 13 ], did not influence seroprevalence rates in waste pickers.…”

Section: Discussioncontrasting

confidence: 71%

Helicobacter Pylori Infection in Waste Pickers: A Case Control Seroprevalence Study

Alvarado‐Esquivel

2013

Gastroenterology Research

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BackgroundThe epidemiology of Helicobacter pylori (H. pylori) infection in waste pickers had not been previously studied. This study aims to determine the association of H. pylori seropositivity and waste picking activity; and to determine socio-demographic, clinical, work, and behavioral characteristics associated with H. pylori seropositivity in waste pickers.MethodsThrough a case-control study design, we examined 90 waste pickers and 90 age- and gender-matched control subjects for the presence of anti-H. pylori IgG antibodies using enzyme-linked immunoassays. Seroprevalence association with socio-demographic, clinical, work and behavioral characteristics of the waste pickers were also investigated.ResultsAntibodies to H. pylori were found in 60 (66.7%) of the 90 waste pickers and in 51 (56.7%) of the 90 controls (P = 0.16). Stratification by age showed that waste pickers aged 14 -30 years old had significantly higher frequency of H. pylori infection than controls of the same age group (56.5% versus 35.6%, respectively; P = 0.04). The seroprevalence of H. pylori infection was not influenced by gender, age, educational level, socioeconomic status, residence, or housing conditions of waste pickers. The presence of underlying diseases and the frequency of gastritis were similar among H. pylori positive and H. pylori negative waste pickers. Logistic regression analysis showed that the duration (years) in the waste picking activity was positively associated with H. pylori exposure (OR = 2.76; 95% CI: 1.22 - 6.25; P = 0.01). In contrast, consumption of alcohol was negatively associated with H. pylori exposure (OR = 0.27; 95% CI: 0.09 - 0.78; P = 0.01). Other work or behavioral characteristics of waste pickers including washing hands before eating, eating from the garbage, animal contacts, consumption of unpasteurized milk, unwashed raw vegetables, fruits, or untreated water, and contact with soil were not associated with H. pylori exposure.ConclusionsThis is the first report on the seroprevalence of H. pylori infection among waste pickers and the factors contributing to such exposure. Results warrant for further research on the potential role of contact with garbage for H. pylori infection.

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“…Cross‐sectional seroprevalence studies place rates of current or past infection between 6%‐85% (Figure ; references:). Random‐effects regression models stratified by age showed the following overall seroprevalence estimates: for children <6 years of age 20% (95% CI: 14%‐25%); for children 6‐11 years old 37% (95% CI: 25%‐49%); for 12‐18 years old 44% (95% CI: 33%‐55%); and overall 33% (95% CI: 27%‐38%).…”

Section: Resultsmentioning

confidence: 99%

Review: Prevalence and dynamics of Helicobacter pylori infection during childhood

et al. 2017

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The prevalence of H. pylori infection varied widely in the studies included here; nevertheless, model estimates by detection type were similar, suggesting that overall, one-third of children worldwide are or have been infected. The few cohort and longitudinal studies available show variability, but most studies, show infection rates over 30%. Rather surprisingly, overall infection prevalence in symptomatic children was only slightly higher, around 40%. Studies including only one positive stool sample should be interpreted with caution as spontaneous clearance can occur.

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The Prevalence of Helicobacter pylori Antibody in Different Age Groups in Central Texas

Cited by 15 publications

References 10 publications

Helicobacter Pylori Infection in Texas Hispanic and Non-Hispanic White Men: Implications for Gastric Cancer Risk Disparities

Helicobacter Pylori Infection in Texas Hispanic and Non-Hispanic White Men: Implications for Gastric Cancer Risk Disparities

Helicobacter Pylori Infection in Waste Pickers: A Case Control Seroprevalence Study

Review: Prevalence and dynamics of Helicobacter pylori infection during childhood

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