The prevalence of metabolic syndrome in premenopausal and postmenopausal women in Southern Thailand

Jeenduang, Nutjaree; Trongsakul, Rangsiri; Inhongsa, Pariwat; Chaidach, Preeyaporn

doi:10.3109/09513590.2014.907261

Cited by 14 publications

(16 citation statements)

References 28 publications

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“…Notably, alterations in gonadal hormones levels represent important risk factors, highly correlated with MetS . Men with low plasma testosterone level have a consistent increase in the CVD risk and women, the incidence of MetS increases after the onset of menopause , because of the decline of plasma oestrogen levels and a relative increase in sex hormone binding globulin (SHBG) and testosterone levels. However, testosterone deficiency can be considered an important marker for CVD and mortality in men, but not in women.…”

Section: Introductionmentioning

confidence: 99%

Testosterone a key factor in gender related metabolic syndrome

Bianchi

Locatelli

2018

Obesity Reviews

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Metabolic syndrome (MetS) is highly correlated with cardiovascular diseases. Although an excess of body fat is a determinant factor for MetS development, a reduced level of testosterone plays a fundamental role in its regulation. Low testosterone level is highly related to insulin resistance, visceral obesity and MetS. We have searched in Pubmed clinical trial with the password: testosterone and insulin resistance, and testosterone and MetS. We found 19 studies on the correlation between testosterone level with insulin resistance and 18 on the effect of testosterone therapy on MetS. A high correlation between low testosterone and insulin resistance has been found in men, but not in women. Testosterone administration in hypogonadal men improved MetS and reduced the mortality risk. Androgen and oestrogen receptors are expressed in adipocytes, muscle and liver tissue, and their activation is necessary to improve metabolic control. Normalization of testosterone level should be the primary treatment in men, along with caloric restriction and physical exercise. These findings come mainly from correlative data, and there remains a need for randomized trials to strengthen this evidence. This review will consider the effects of testosterone on the regulation and development of MetS in men and women.

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Section: Introductionmentioning

confidence: 99%

Testosterone a key factor in gender related metabolic syndrome

Bianchi

Locatelli

2018

Obesity Reviews

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“…Metabolic syndrome affects more than 30% of the population over the age of 50 years, and women have three times a greater risk of mortality and morbidity due to cardiovascular disease (3). Previous studies have indicated that the prevalence of metabolic syndrome has increased in postmenopausal women, and it has been reported that its prevalence is between 16% and 69% in different societies (4). Abdominal obesity and a low HDL cholesterol level are considered to be the main factors increasing metabolic syndrome prevalence in postmenopausal women (5,6).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Metabolic Syndrome and Effect of Hormone Profile in Postmenopausal Patients

Şahin¹,

Salman²,

Ayanoğlu³

et al. 2016

JAREM

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Objective: The purpose of this study was to evaluate the prevalence and connection with hormonal changes of metabolic syndrome and its components in postmenopausal women based on a literature survey. Methods:The medical records of 138 postmenopausal patients were retrospectively reviewed between January 2013 and March 2014. Patients with surgical menopause and those who underwent hormone replacement therapy, chemotherapy, and radiotherapy were excluded. Metabolic syndrome was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria. Patients' demographic data, menopausal status, medical history, and physical examination and clinical laboratory data were analyzed. Data were evaluated statistically.Results: In total, 128 patients were included in this study. The menopausal age of patients in the metabolic syndrome group was 50.06±2.93 and that in the non-metabolic syndrome group was 45.16±4.4 years. The prevalence of metabolic syndrome was observed in 43.4% patients in this study. A statistically significant negative high correlation (p<0.05) was observed between waist circumference and the number of metabolic components with FSH-LH levels. Conclusion:The prevalence of metabolic syndrome among postmenopausal women is high, and abdominal obesity and low HDL levels are strong predictors. These components can lead to an increase in cardiovascular diseases. Thus, it is encouraging to adopt lifestyle changes that reduce the prevalence of metabolic syndrome. (JAREM 2016; 6: 35-9)

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“…This trend is also observed in Korean [36], Indian [34], Spanish [37] etc., which may be partly attributed to hormone secretion. According to Jeenduang's study, prevalence of MetS was 29.37% in postmenopausal women, while was 16.97% in premenopausal women [38]. Hormones hidden behind menopause may lead to this alteration [39].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Associated Factors of Metabolic Syndrome in Chinese Middle-Aged and Elderly Population: A Nationally Cross-Sectional Study

Xiong

Zhang

Wen

et al. 2021

Preprint

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Background: Currently, China has an increasingly aging population. However, the prevalence of metabolic syndrome (MetS) in this high-risk population for metabolic diseases remains unknown. To investigate the age and gender specific prevalence and associated factors of MetS in Chinese middle-aged and elderly population, we did the study on it. Methods: Data were retrieved from China Health and Retirement Longitudinal Study (CHARLS) and subjected to descriptive statistics. Further, univariate logistic regression was used to evaluate the relevant factors, and then multivariate logistic regression was selected to construct the final model. Results: In present study, a total of 10,834 participants were included. The overall prevalence of MetS was 32.97% as defined by International Diabetes Federation and 29.75% under National Cholesterol Education Program - The Adult Treatment Panel III criteria. With aging, prevalence of MetS descended in males, while ascended in females. In the >70 years old group, the prevalence of MetS was three times higher in females than that in males (50.43% versus 16.03%). Across all age groups and sexes, the prevalence of MetS in urban areas was significantly higher than in rural areas. In addition, regardless of gender, the prevalence was highest for those living in the north region (28.41% for males & 51.74% for females) and lowest for those living in the southwest region (13.91% for males & 31.58% for females). Finally, two specific correlates, afternoon nap and blood urea nitrogen (BUN), were identified in present study (P < 0.05). Conclusion: The prevalence of MetS varied in different age groups, sexes, living areas and regions and was associated with afternoon nap and BUN.

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The prevalence of metabolic syndrome in premenopausal and postmenopausal women in Southern Thailand

Abstract: The prevalence of MetS is higher in postmenopausal women than in premenopausal women, and its significant predictors include age and BMI.

Cited by 14 publications

References 28 publications

Testosterone a key factor in gender related metabolic syndrome

Testosterone a key factor in gender related metabolic syndrome

Prevalence of Metabolic Syndrome and Effect of Hormone Profile in Postmenopausal Patients

Prevalence and Associated Factors of Metabolic Syndrome in Chinese Middle-Aged and Elderly Population: A Nationally Cross-Sectional Study

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