The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration

Sachdev, Perminder S.; Lipnicki, Darren M.; Kochan, Nicole A.; Crawford, John D.; Thalamuthu, Anbupalam; Andrews, Gavin; Brayne, Carol; Matthews, Fiona E.; Stephan, Blossom C. M.; Lipton, Richard B.; Katz, Mindy J.; Ritchie, Karen; Carrière, Isabelle; Ancelin, Marie-Laure; Lam, Linda Chiu Wa; Wong, Candy; Fung, Ada Wai Tung; Guaita, Antonio; Vaccaro, Roberta; Davin, Annalisa; Ganguli, Mary; Dodge, Hiroko H.; Hughes, Tiffany F.; Anstey, Kaarin J.; Cherbuin, Nicolas; Butterworth, Peter; Ng, Tze Pin; Gao, Qi; Reppermund, Simone; Brodaty, Henry; Schupf, Nicole; Manly, Jennifer J.; Stern, Yaakov; Lobò, Antonio; López-Antón, Raúl; Santabárbara, Javier

doi:10.1371/journal.pone.0142388

Cited by 270 publications

(209 citation statements)

References 63 publications

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“…There is no consensus on how each neuropsychological test should be allocated to a specific cognitive domain as such tests are generally multifactorial. Table 2 shows the list of tests used in the studies under five cognitive domains; each test was assigned to a cognitive domain based on convention and previous work such as for COSMIC [63]. Demographic effects such as age, gender, and education need to be accounted for.…”

Section: Discussionmentioning

confidence: 99%

STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease

Sachdev

Crawford

et al. 2016

Alz & Dem Diag Ass & Dis Mo

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IntroductionThe Stroke and Cognition consortium (STROKOG) aims to facilitate a better understanding of the determinants of vascular contributions to cognitive disorders and help improve the diagnosis and treatment of vascular cognitive disorders (VCD).MethodsLongitudinal studies with ≥75 participants who had suffered or were at risk of stroke or TIA and which evaluated cognitive function were invited to join STROKOG. The consortium will facilitate projects investigating rates and patterns of cognitive decline, risk factors for VCD, and biomarkers of vascular dementia.ResultsCurrently, STROKOG includes 25 (21 published) studies, with 12,092 participants from five continents. The duration of follow-up ranges from 3 months to 21 years.DiscussionAlthough data harmonization will be a key challenge, STROKOG is in a unique position to reuse and combine international cohort data and fully explore patient level characteristics and outcomes. STROKOG could potentially transform our understanding of VCD and have a worldwide impact on promoting better vascular cognitive outcomes.

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Section: Discussionmentioning

confidence: 99%

STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease

Sachdev

Crawford

et al. 2016

Alz & Dem Diag Ass & Dis Mo

Self Cite

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“…The prevalence of MCI is estimated to be around 5.0% to 36.7% 9. This difference in prevalence range is explained by the age of the patients, where older patients were found to have higher prevalence of MCI and younger patients have lower prevalence of MCI 10.…”

Section: Definitions and Diagnostic Criteriamentioning

confidence: 99%

Mild cognitive impairment in primary care: a clinical review

Assaf

Tanielian

2018

Postgraduate Medical Journal

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Dementia is projected to become a global health priority but often not diagnosed in its earlier preclinical stage which is mild cognitive impairment (MCI). MCI is generally referred as a transition state between normal cognition and Alzheimer’s disease. Primary care physicians play an important role in its early diagnosis and identification of patients most likely to progress to Alzheimer’s disease while offering evidenced-based interventions that may reverse or halt the progression to further cognitive impairment. The aim of this review is to introduce the concept of MCI in primary care through a case-based clinical review. We discuss the case of a patient with MCI and provide an evidence-based framework for assessment, early recognition and management of MCI while addressing associated risk factors, neuropsychiatric symptoms and prognosis.

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“…In the MHCC report, mild cognitive impairment (MCI) individuals were counted together with dementia cases. However, some estimates stated that 39-60% of individuals with MCI will progress to dementia [20][21][22][23]. In other reports where MCI and dementia are included together, the estimation would be approximately 50% more than if dementia alone was included in the estimate.…”

Section: Dementia In Canadamentioning

confidence: 99%

Future Trends and the Economic Burden of Dementia in Manitoba: Comparison with the Rest of Canada and the World

2018

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Dementia is a growing public health concern in Canada. This epidemic is linked to huge human and economic costs. The number of Manitobans (65+) with dementia in 2045 (47,021), representing 2.58% of the Manitoban population, will be 2.3 times that of the year 2015 (20,235). The number of cases of dementia in Manitoba grew by 20.7% from 2015 to 2025, 68.16% from 2015 to 2035 and at an alarming rate of 125% from 2015 to 2045. Importantly, the total economic burden of dementia in Manitoba is close to one billion USD and is expected to grow more than 28 billion USD during the year 2038. The focus of this review is to compare dementia rates and the financial burden of dementia in Manitoba with the rest of Canada and the world from 2012 to 2048.

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The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration

Cited by 270 publications

References 63 publications

STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease

STROKOG (stroke and cognition consortium): An international consortium to examine the epidemiology, diagnosis, and treatment of neurocognitive disorders in relation to cerebrovascular disease

Mild cognitive impairment in primary care: a clinical review

Future Trends and the Economic Burden of Dementia in Manitoba: Comparison with the Rest of Canada and the World

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