The prevalence of non-vascular pulmonary manifestations in Takayasu’s Arteritis patients: A Retrospective multi-centred Turkish cohort study

Yazıcı, Ayten; Tahra, Sema Kaymaz; Işık, Ö. Özdemir; Kara, Mete; Alpay-Kanitez, Nilufer; Gerçik, Önay; Omma, Ahmet; Kocaer, Sinem Burcu; Kalkan, Kübra Erol; Bi̇lgi̇n, N; Aksu, Kenan; Keser, Gökhan; Akar, Servet; Önen, Fatoş; Emmüngil, Hakan; Kaşifoğlu, Timuçin; Alıbaz-Öner, Fatma; Direşkeneli, Haner; Çefle, Ayşe

doi:10.1080/03009742.2021.1972535

Cited by 3 publications

(2 citation statements)

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“…If the diagnosis and treatment are delayed, the pulmonary artery pressure can increase gradually, and the best treatment opportunity can be missed, resulting in a decline in activity tolerance and seriously affecting the quality of life of patients. Thus, to reduce misdiagnosis and mistreatment and improve the prognosis of patients, clinicians should improve their awareness of the early diagnosis of the disease, and pay attention to the symptoms, signs, and auxiliary examination results of TA complicated by PAI (27)(28)(29). A limitation of this study is that the number of cases was so small that the clinical value is not significant.…”

Section: Discussionmentioning

confidence: 88%

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Clinical characteristics of pulmonary artery involvement in patients with Takayasu arteritis between pulmonary hypertension and non-pulmonary hypertension

Lei¹,

Li²,

Wang³

et al. 2023

Ann Transl Med

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Background: Multiple Takayasu arteritis (TA) is a chronic non-specific large to medium vasculitis disease that mainly accumulates the aorta and its branches. Pulmonary vascular disease is often seen as stenosis and occlusion, and patients may show no moderate to severe pulmonary hypertension. The study sought to summarize the clinical characteristics of patients with pulmonary hypertension (PH) involving the pulmonary artery caused by TA.Methods: Twenty-nine patients with TA treated at the General Hospital of Ningxia Medical University from September 2009 to December 2021 were collected. All the patients had TA involving the pulmonary artery, and were divided into the PH group (n=17 patients) and the non-PH group (n=12). The diagnoses of pulmonary Takayasu arteritis (PTA) were used the 1990 diagnostic criteria of the American Rheumatic Association and the 1996 improved Ishikawa diagnostic criteria. Computed tomography angiography (CTA) of the patients after treatment was determined, and the laboratory tests, echocardiography, pulmonary and systemic artery angiography were assessed. Results:The patients had an average age of onset of 33.5 [19-60] years. All the cases of PH were confirmed by echocardiography and it was suggested that the bilateral side easier to involve pulmonary arteries than the unilateral side, and the right side than the left side. At admission, the ESR and N pro-BNP level of the PH group did not differ significantly to those of the non-PH Group. There were significant differences between the two groups in patients in terms of the type II of TA imaging diagnosis (P=0.030). The accuracy of diagnosing PH with bilateral pulmonary vascular involvement was significantly higher in the PH group than the non-PH group (P=0.003). The diagnostic accuracy of pulmonary vascular lumen obstruction in the PH group was significant difference (P<0.05). The diagnostic accuracy of pleural effusion in the PH group was significantly higher than that of the non-PH group (P=0.001) for lung field signs. The diameters of the right atrium and pulmonary artery differed significantly between the two groups (P=0.013).Conclusions: Patients with TA involving the pulmonary artery mainly complained of shortness of breath.Most of these patients had PH.

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Section: Discussionmentioning

confidence: 88%

“…In this study, the 3 patients referred to the 1996 standard (25). Under the standard, the bilateral subclavian artery injury must display typical TA symptoms for >1 month to meet the conditions of pulmonary artery injury (lobar branch injury, segmental branch obstruction, or stenosis) (26)(27)(28)(29).…”

Section: Discussionmentioning

confidence: 99%