The prevalence of potentially inappropriate medication prescribing in elderly patients with chronic kidney disease

Jones, Sarah; Bhandari, Sunil

doi:10.1136/postgradmedj-2012-130889

Cited by 62 publications

(68 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[4][5][6] In the present study, more than 85% of patients experienced at least one medication error that is comparable to reported medication error rates in CKD patients by other researchers. 7 In our survey, the rates of medication errors were 3.5 errors per patient and 0.18 errors per ordered medication that is more than those reported from the infectious disease ward of the same hospital (0.3 errors per patient and 0.05 errors per ordered drug).…”

Section: Discussionsupporting

confidence: 75%

“…[4][5][6][7][8]13,[17][18][19][20] There major limitations of the present study that should be addressed include cross-sectional nature of this study and lack of including hospitals which are deprived clinical pharmacy services as a control group and assessing medication errors only in nephrology wards of one hospital that makes it difficult to extrapolate the findings to other wards or the same ward of other institutions. The other limitation is the estimation, but not the exact evaluation of direct medication cost in this study.…”

Section: Discussionmentioning

confidence: 99%

“…3 Medication errors, as a subgroup of drugrelated problems, are highly prevalent among chronic kidney disease (CKD) and dialysis patients due to altered drugs' pharmacokinetics, presence of multiple complex co-morbidities, polypharmacy, and high susceptibility to drug toxicity. [4][5][6] Some reports show that more than 85% of CKD patients experience at least one medication error. 7 Untreated indications and incorrect dosage are common types of medication errors among CKD and hemodialysis patients.…”

Section: Introductionmentioning

confidence: 99%

“…[5][6][7][8][9] Clinical pharmacists play important roles in detection and prevention of medication errors. [4][5][6][7][8] Clinical pharmacy services started during last two decades in a few teaching hospitals in Iran. There are few reports on medication errors surveillance in hospitalized patients in Iran and clinical pharmacists' interventions to prevent or reduce these errors.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Frequency, types, and direct related costs of medication errors in an academic nephrology ward in Iran

et al. 2014

View full text Add to dashboard Cite

Medication errors are ongoing problems among hospitalized patients especially those with multiple co-morbidities and polypharmacy such as patients with renal diseases. This study evaluated the frequency, types and direct related cost of medication errors in nephrology ward and the role played by clinical pharmacists. During this study, clinical pharmacists detected, managed, and recorded the medication errors. Prescribing errors including inappropriate drug, dose, or treatment durations were gathered. To assess transcription errors, the equivalence of nursery charts and physician's orders were evaluated. Administration errors were assessed by observing drugs' preparation, storage, and administration by nurses. The changes in medications costs after implementing clinical pharmacists' interventions were compared with the calculated medications costs if the medication errors were continued up to patients' discharge time. More than 85% of patients experienced medication error. The rate of medication errors was 3.5 errors per patient and 0.18 errors per ordered medication. More than 95% of medication errors occurred at prescription nodes. Most common prescribing errors were omission (26.9%) or unauthorized drugs (18.3%) and low drug dosage or frequency (17.3%). Most of the medication errors happened on cardiovascular drugs (24%) followed by vitamins and electrolytes (22.1%) and antimicrobials (18.5%). The number of medication errors was correlated with the number of ordered medications and length of hospital stay. Clinical pharmacists' interventions decreased patients' direct medication costs by 4.3%. About 22% of medication errors led to patients' harm. In conclusion, clinical pharmacists' contributions in nephrology wards were of value to prevent medication errors and to reduce medications cost.

show abstract

Section: Discussionsupporting

confidence: 75%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Frequency, types, and direct related costs of medication errors in an academic nephrology ward in Iran

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Penelitian yang dilakukan oleh Jones & Bhandari (2013) menunjukan tingkat kejadian PIMs pada pasien usia lanjut dengan CKD sebesar 56%. PIMs pada pasien usia lanjut dengan gagal ginjal kronik di Jepang mencapai 57% (Kondo et al, 2014).…”

Section: Pendahuluanunclassified

Hubungan Jumlah Obat Yang Diresepkan Dengan Potensial Penggunaan Obat Yang Tidak Tepat Pada Pasien Ckd Di Rs Pku Muhammadiyah Yogyakarta

Mulyani

Darmawan²,

Mustofa³

2015

Pharmaciana

View full text Add to dashboard Cite

ABSTRAKPenurunan fungsi fisiologis tubuh terkait usia meyebabkan beberapa masalah kesehatan pada usia lanjut, sehingga masalah pengobatan pada usia lanjut juga tidak jarang ditemukan seperti polifarmasi dan potentially inappropriate medication (PIMs). Tujuan penelitian ini untuk mengetahui hubungan jumlah obat yang diresepkan dengan PIMs pada pasien usia lanjut yang menderita penyakit ginjal kronis di RS PKU Muhammadiyah Yogyakarta. Identifikasi PIMs dilakukan dengan kriteria STOPP, sedangkan jumlah obat yang diresepkan dilihat berdasarkan buku kendali obat pasien. Untuk mengkaji riwayat kesehatan pasien dilakukan wawancara dan penelusuran rekam medik. Karakteristik pasien di analisa secara deskriptif, sedangkan korelasi antar variabel dianalisis dengan uji chi square. Dari 53 sampel, teridentifikasi PIMs sebesar 17% dengan rata-rata sampel mendapatkan satu PIMs. Sedangkan dari 410 obat yang diresepkan rata-rata pasien menerima obat 8 obat (>6). Hasil uji bivariat menunjukan bahwa tidak terdapat hubungan yang signifikan antara jumlah obat yang diresepkan dengan PIMs.Kata kunci : Jumlah obat yang diresepkan, PIMs, CKD. ABSTRACTAge-related decrease of physiological function caused some healt problem in elderly, so the problem of treatment in the elderly is also not uncommon found as polypharmacy and Potentially Inappropriate medication (PIMs). The purpose of this study to determine the relationship of the number of drug prescribed with PIMs in elderly patients with CKD in PKU Muhammadiyah Yogyakarta Hospital. PIMs identification by STOPP criteria, while the number of drugs prescribed seen by drugs control books. To assess the patient's medical history by interviews and search records. Patient characteristics were analyzed descriptively, correlations between variables were analyzed with chi square test. From 53 samples, PIMs identified 17% and average one sample got one PIMs, while of the 410 drugs that prescribed average patient receiving 8 drugs (> 6). Bivariate test results showed that no significant relationship between the number of drug prescribed with PIMs.

show abstract

Potentially inappropriate medications prescribing to elderly patients with advanced chronic kidney by using 2019 American Geriatrics Society Beers Criteria

Chahine

2020

Health Science Reports

View full text Add to dashboard Cite

Background and aimsA potentially inappropriate medication (PIM) is defined as a drug‐carrying risks outweighing the expected clinical benefits. Elderly patients with chronic kidney disease (CKD) are particularly at higher risk of drug‐related toxicities. In Lebanon, no studies have been conducted regarding the prescribing of PIMs in hospitalized CKD patients. This study aimed to check the prevalence of PIMs using the American Geriatrics Society (AGS) Beers criteria in elderly patients with advanced CKD stages including dialysis and to identify possible risk factors that may be associated with prescribing PIMs in this population.MethodsA retrospective cross‐sectional study was conducted on patients with advanced CKD above the age of 65 years and admitted between January 2019 and June 2019 to two University Hospitals in Beirut, Lebanon. We used multiple logistic regression analysis to determine which factors were associated with prescription of PIMs according to AGS Beers criteria‐2019.ResultsThe study sample included 199 patients with renal dysfunction, 75.9% were aged 70 years or more, 53.8% were females, and 61.8% were prescribed five drugs or more. Eighty‐two patients were receiving hemodialysis (41.2%). PIMs prevalence was 34.1% (68/199 patients) according to Beers criteria in elderly patients with advanced CKD stages.The most frequently prescribed PIMs were ranitidine (39.1%), enoxaparin (25%), tramadol (9.8%), and ciprofloxacin (5.4%). Polypharmacy (OR 2.1, CI 95% 1.58‐2.79), a higher number of comorbidities (OR 3.01, CI 95% 1.43‐6.30), and coronary artery diseases (OR 3.14 CI 95% 1.44‐6.85) were the factors associated with an increased risk of at least one PIM prescription.ConclusionOur study found that one out of three patients with advanced CKD had at least one PIM according to the latest Beers criteria. A large proportion of inappropriate prescribing is preventable by increasing awareness of prescribing physicians to the explicit lists of PIMs.

show abstract

The prevalence of potentially inappropriate medication prescribing in elderly patients with chronic kidney disease

Cited by 62 publications

References 17 publications

Frequency, types, and direct related costs of medication errors in an academic nephrology ward in Iran

Frequency, types, and direct related costs of medication errors in an academic nephrology ward in Iran

Hubungan Jumlah Obat Yang Diresepkan Dengan Potensial Penggunaan Obat Yang Tidak Tepat Pada Pasien Ckd Di Rs Pku Muhammadiyah Yogyakarta

Potentially inappropriate medications prescribing to elderly patients with advanced chronic kidney by using 2019 American Geriatrics Society Beers Criteria

Contact Info

Product

Resources

About