The prevalence of restless legs syndrome in Edirne and its districts concomitant comorbid conditions and secondary complications

Abstract

We aimed to determine the prevalence and risk factors of restless legs syndrome in Edirne and its districts, located in Western Thrace, which is the most western part of Turkey. In this study, 4003 individuals who could communicate and agreed to participate in the study were evaluated. To obtain the data from the applicants in 30 Family Health Centres in Edirne and its districts, a face-to-face questionnaire that consisted of 54 questions was prepared by the researchers. The questionnaire included general information, questions to evaluate potential concomitant comorbid conditions and questions regarding the symptomatology used in restless legs syndrome (RLS) diagnosis, as well as questions to evaluate insomnia and tension-type headache secondary to insomnia according to the ICD-II Criteria (International Classification of Sleep Disorders-II Criteria). Of 4003 individuals, 282 were diagnosed with RLS according to the questionnaire results from Edirne and its districts, and the prevalence of RLS was 7%. Approximately, 47.9% of the patients with RLS were male, and 52.1% were female, which was not significantly different (p > 0.05). Anaemia was identified in 41.1 % of the cases and control group was detected in 19.4 %, which was significantly different (p < 0.001). Secondary insomnia was identified in 64.2% of the cases with RLS and was not detected in 35.8%, which was significantly different (p < 0.001). RLS prevalence studies will increase the awareness of the community and provide early diagnosis and treatment, as well as serve as a basis to reduce morbidity and improve the quality of life.

Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population

“…In the 6 studies in which set-of-symptoms criteria using a questionnaire were adopted, the RLS prevalence ranged from 4.5 to 9.7% [22-25, 38, 39]. In the 10 studies in which RLS was defined by the presence of 4 essential clinical features through a direct interview, the prevalence ranged from 0.1 to 10.2% and was lower than 6% (0.1-5.5%) in the majority of studies (6 of 10 studies) [12][13][14][40][41][42][43][44][45][46]. A differential diagnosis was additionally applied in 12 studies; in these studies, including ours, the prevalence ranged from 0.4 to 8.3% [15-18, 20, 21, 47-51].…”

Erzurum İli Huzursuz Bacak Sendromu Prevelansının Araştırılması ve Sosyodemografik Özelliklerin İncelenmesi

“…Çalışmamız tiroid bozukluğu olan olgularda HBS ile ilişkisinin olmadığı yönünündeydi. Literatürde HBS' li hastaların %21'inde DM olduğu gösterilmiştir, [9] yine HBS semptomları esnasında kalp hızında ve kan basıncında artış olduğu tespit edilmiştir. [10,29] DM ve HT'nin HBS ile ilişkisinin gösterildiği çalışmalar haricinde hiperlipidemi ile ilişkisini savunan çalışmalarda vardır.…”

“…[12,13] Bunun yanı sıra cinsiyet, yaş, genetik yatkınlık ve komorbid durumlar (anemi, hipertansiyon, diyabet, hiperkolesterolemi, depresif bozukluk, tiroid, akciğer ve böbrek hastalıkları) hakkında çalışmalar yapılmıştır. [9,10,[14][15][16][17][18][19] Biz çalışmamızda Erzurum ilinde HBS prevalansını, olguların sosyodemografik özelliklerini, yaş ve cinsiyete göre dağılımlarını, sigara ve alkol kullanımı ve komorbid durumlar ile ilişkisini belirlemeyi amaçladık. Bunun yanı sıra olgularda semptomların şiddet oranları IRLSSGRS (Uluslararası Huzursuz Bacak Sendromu Çalışma Grubu Şiddet Skalası) kullanarak değerlendirdik.…”

Restless Legs Syndrome in Patients with Epilepsy Under Levetiracetam Monotherapy

“…Many epidemiological studies from different parts of Turkey were also published. RLS was observed as 3.19%, 4.5%, 7% and 3.4% in reports from Mersin (southern part of country) (26), Trabzon (northeast Black Sea Region of Turkey) (27), Edirne (Western part of Turkey) (28) and Kandira (Western Black Sea coast) (7) respectively. Interestingly, the highest ratio for RLS was observed in Edirne, the northwest part of the Turkey.…”