Postoperative infection is the commonest complication that causes failure of spinal surgery. Although the rate of infection after cervical surgery is lower than that after lumbar surgery, the absolute number of cases is increasing. In recent years, new techniques, such as serum amyloid A and fludeoxyglucose ( 18 F) positron emission tomography (18F-FDG PET), have emerged and gradually been employed in the diagnosis of postoperative infection, updating the ability to identify the presence of infection. Most patients with cervical postoperative infection require re-operation. There are three principles for such surgery: thorough debridement, adequate drainage and ensuring stability of the spine. Some severe cases even need emergency surgery. This article aims to discuss the controversial issues in diagnosis and treatment of cervical postoperative infection, as well as progress in related studies.Key words: Cervical vertebrae; Diagnosis; Infection; Surgical procedures, operative; Therapy Cervical postoperative infections occur after cervical spine surgery and other invasive operations. The incidence of cervical postoperative infection is lower than that of postoperative infection of other parts of the spine. However, in recent years with the increasing amount of cervical spine surgery and the launching of new treatment, the absolute number of cases has increased, which has drawn more clinical attention to this issue.It has been reported that the infection rate after anterior cervical surgery is in the 0-1% range 1,2 , and that posterior cervical surgery operation has a relatively higher risk of infection, about 1% with simple decompression and 4.5-9% with internal fixation 3,4 .
Classificationo s4_140 152..157Cervical postoperative infection is classified as superficial or deep according to the level of infection 5 . Superficial infection is limited to the skin and subcutaneous layers, and does not involve the deep fascia. Deep infection refers to the infection in the deep fascia (nuchal ligament and platysma muscle) and involves muscle and its underlying compartments. Deep infection includes intervertebral disc inflammation (also called intervertebral space infection), vertebral osteomyelitis and epidural abscess. Cervical postoperative infection can also be classified according to its time of occurrence as early (within 3 weeks of the operation) and late-onset infection (more than 4 weeks after surgery).