The Preventive Effect of Lactobacillus plantarum ZS62 on DSS-Induced IBD by Regulating Oxidative Stress and the Immune Response

Pan, Yanni; Ning, Yujing; Hu, Jing; Wang, Zhiying; Chen, Xiufeng; Zhao, Xin

doi:10.9734/bpi/mono/978-93-5547-256-4/ch2

Cited by 4 publications

(6 citation statements)

References 17 publications

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“…The surface density of immunofluorescent proteins ZO-1 and MUC-2 was measured and calculated as follows: 15 An Eclipse CI-L fluorescence photography microscope was used to select the target area of tissues for 200-fold imaging. After the imaging was completed, image-Pro Plus 6.0 analysis software was used to convert green/red fluorescent monochrome photos into black and white pictures, and then the same black was selected as the unified standard to judge the positivity of all photos.…”

Section: Methodsmentioning

confidence: 99%

“…Finally, sections (4 µm sections) were made and they were stained with hematoxylin and eosin (H&E), based on previous studies. 15 Then, a light microscope was used for observation and photography and a modification of the previous scoring scale to assess the histological damage score (Table S2 †). 16 Mucin2 and ZO-1 antibodies were labeled with fluorescein separately.…”

Section: Papermentioning

confidence: 99%

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Lactobacillus plantarumHNU082 alleviates dextran sulfate sodium-induced ulcerative colitis in mice through regulating gut microbiome

Liu

et al. 2022

Food Funct.

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Section: Methodsmentioning

confidence: 99%

Section: Papermentioning

confidence: 99%

Lactobacillus plantarumHNU082 alleviates dextran sulfate sodium-induced ulcerative colitis in mice through regulating gut microbiome

Liu

et al. 2022

Food Funct.

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“…The antioxidant system mainly plays a role in scavenging ROS and includes enzymatic and nonenzymatic systems. Among these, the enzymatic system mainly refers to antioxidant enzymes such as SOD and CAT (Pan et al, 2021). In our experiments, we measured the levels of several antioxidant enzymes that could scavenge ROS, including SOD, CAT, GPx, and GSH.…”

Section: Discussionmentioning

confidence: 99%

Alleviation of oxidative stress in pancreatic tissue of hyperglycemic mice by Lactiplantibacillus plantarum SCS4

Meng

Chen

Sun

et al. 2022

Journal of Food Biochemistry

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This study aimed to investigate the effect of Lactiplantibacillus plantarum SCS4 in alleviating oxidative stress in the pancreatic tissue of hyperglycemic mice. A total of 90 six-week-old specific pathogen-free male Kunming mice were randomly divided into six groups [normal group (NG), blank control group (MG), phosphate-buffered saline (PBS) control group (CG), SCS4 first control group (DT1), SCS4 second control group (DT2), and SCS4 third control group (DT3)]. Except the NG group, in the other five groups, streptozotocin (STZ) was intraperitoneally injected for five consecutive days to establish a hyperglycemia model; the concentration of STZ was 50 mg/kg (bw). After successful modeling, DT1, DT2, and DT3 mice were administered 0.2 ml of L. plantarum SCS4 bacterial solution (10 10 colony forming unit/ml), the cellular content of L. plantarum SCS4, and the inactivated cellular content of L. plantarum SCS4, respectively. Furthermore, 0.2 ml of PBS was given to mice in the CG group for control. The levels of insulin (INS), reactive oxygen species (ROS), malondialdehyde (MDA), and antioxidant enzymes such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) were measured by enzyme-linked immunosorbent assay, and the morphology of the pancreas was observed. The results showed that after 10 weeks of gavage treatment, the level of INS in the DT3 group significantly increased to 6.36 mIU/L compared with that in the MG group (p < .05). Meanwhile, the levels of ROS and MDA of DT3 returned to normal levels of 291.07 IU/ml and 4.29 mnol/L, respectively. The activities of various antioxidant enzymes increased. The levels of SOD, CAT, and GPx in DT3 were the closest to the levels in NG. In addition, the pathological sections showed that the degree of pancreatic tissue lesions was relatively more severe in the MG group than in the NG group. The degree of pancreatic tissue lesions was relatively less severe in the DT2 group than in the MG group, and no significant lesion was seen in the DT3 group. Our results indicated that the inactivated bacterial content of L. planetarium SCS4 was more effective in improving oxidative stress in the pancreas of hyperglycemic mice.

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“…Consuming probiotics and prebiotics and maintaining good eating habits Probiotics and prebiotics improve gut microbiota and reduce oxidative stress and inflammation (Goulet, 2015;O'Hara & Fergus, 2015;Y. Pan et al, 2021).…”

Section: 23mentioning

confidence: 99%

“…Probiotics and prebiotics improve gut microbiota and reduce oxidative stress and inflammation (Goulet, 2015; O'Hara & Fergus, 2015; Y. Pan et al., 2021). According to Zhang et al.…”

Section: Mitigation Strategies Of Dityrosinementioning

confidence: 99%

Dityrosine in food: A review of its occurrence, health effects, detection methods, and mitigation strategies

Yang

Ding

et al. 2022

Comp Rev Food Sci Food Safe

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Protein and amino acid oxidation in food products produce many new compounds, of which the reactive and toxic compound dityrosine, derived from oxidized tyrosine, is the most widely studied. The high reactivity of dityrosine enables this compound to induce oxidative stress and disrupt thyroid hormone function, contributing to the pathological processes of several diseases, such as obesity, diabetes, cognitive dysfunction, aging, and age‐related diseases. From the perspective of food safety and human health, protein‐oxidation products in food are the main concern of consumers, health management departments, and the food industry. This review highlights the latest research on the formation pathways, toxicity, detection methods, occurrence in food, and mitigation strategies for dityrosine. Furthermore, the control of dityrosine in family cooking and food‐processing industry has been discussed. Food‐derived dityrosine primarily originates from high‐protein foods, such as meat and dairy products. Considering its toxicity, combining rapid high sensitivity dityrosine detection techniques with feasible control methods could be an effective strategy to ensure food safety and maintain human health. However, the current dityrosine detection and mitigation strategies exhibit some inherent characteristics and limitations. Therefore, developing technologies for rapid and effective dityrosine detection and control at the industrial level is necessary.

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The Preventive Effect of Lactobacillus plantarum ZS62 on DSS-Induced IBD by Regulating Oxidative Stress and the Immune Response

Cited by 4 publications

References 17 publications

Lactobacillus plantarumHNU082 alleviates dextran sulfate sodium-induced ulcerative colitis in mice through regulating gut microbiome

Lactobacillus plantarumHNU082 alleviates dextran sulfate sodium-induced ulcerative colitis in mice through regulating gut microbiome

Alleviation of oxidative stress in pancreatic tissue of hyperglycemic mice by Lactiplantibacillus plantarum SCS4

Dityrosine in food: A review of its occurrence, health effects, detection methods, and mitigation strategies

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