The PRIMA (PRoton IMAging) collaboration: Development of a proton Computed Tomography apparatus

The use of charged particles and nuclei in cancer therapy is one of the most successful cases of application of nuclear physics to medicine. The physical advantages in terms of precision and selectivity, combined with the biological properties of densely ionizing radiation, make charged particle approach a clinically preferred choice in a number of cases. Hadron therapy is in continuous development and nuclear physicists can give important contributions to this discipline. In this work, some of the relevant aspects in nuclear physics will be reviewed. ARTICLE HISTORY

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“…[50,51]. The scanner is based on a tracker and a calorimeter to measure single protons trajectories and their residual energy.…”

Section: Imaging For Hadron Therapy: Proton Computed Tomographymentioning

confidence: 99%

Nuclear physics and particle therapy

Battistoni

Mattei

Muraro

2016

Advances in Physics: X

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“…An example of the research and development work for a prototype of proton Computed Tomography (pCT) is described in ref. [9,10]. The scanner Figure 1: Example of pCT test results for inhomogeneous phantom [10].…”

Section: Imaging For Hadron Therapy: Proton Computed Tomographymentioning

confidence: 99%

Nuclear physics and particle therapy

Battistoni

2016

EPJ Web of Conferences

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The use of charged particles and nuclei in cancer therapy is one of the most successful cases of application of nuclear physics to medicine. The physical advantages in terms of precision and selectivity, combined with the biological properties of densely ionizing radiation, make charged particle approach an elective choice in a number of cases. Hadron therapy is in continuous development and nuclear physicists can give important contributions to this discipline. In this work some of the relevant aspects in nuclear physics will be reviewed, summarizing the most important directions of research and development.

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“…This number has to be multiplied by a factor of the order of 36-72 to uniformly cover the entire 360 o ending to a total acquisition time of the order of one minute. A detailed discussion about this new prototype is given in [19,20].…”

Section: Up-graded Systemmentioning

confidence: 99%

The PRIMA (Proton Imaging) collaboration: Status of the development of a proton Computed Tomography Scanner

Bruzzi¹,

Brianzi²,

Bucciolini

et al. 2012

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)

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Abstract-The PRIMA (Proton IMAging) experiment is aimed at developing a proton Computed Tomography (pCT) prototype based on tracking single protons. Approaches to the pCT consist in the use of silicon microstrip detectors to measure the position and direction of individual protons before and after they traverse the phantom, in view to reconstruct the trajectory of each proton, and a calorimeter for measuring particle residual energy. A small prototype was tested, under 62 MeV proton beam at Laboratory Nazionali del Sud, (Catania Italy) and under 180 MeV proton beam at Svedberg Laboratories, Uppsala Universitet, (Uppsala Sweden). Several experiments concerning proton imaging, tomography and radiography, were carried out during these beam tests. Radiographies have been reconstructed with different methods: results show the good performances of the device, with spatial resolution fulfilling the stringent requirements of a pCT device.

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The PRIMA (PRoton IMAging) collaboration: Development of a proton Computed Tomography apparatus

Cited by 37 publications

References 16 publications

Nuclear physics and particle therapy

Nuclear physics and particle therapy

Nuclear physics and particle therapy

The PRIMA (Proton Imaging) collaboration: Status of the development of a proton Computed Tomography Scanner

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