The Primary Prevention of Coronary Heart Disease in Women

Rich‐Edwards, Janet W.; Manson, JoAnn E.; Hennekens, Charles H.; Buring, Julie E.

doi:10.1056/nejm199506293322607

Cited by 343 publications

(139 citation statements)

References 129 publications

Supporting

Mentioning

127

Contrasting

Unclassified

Order By: Relevance

“…Avoidance of excess weight and obesity is important for lowering the risk of chronic diseases such as coronary heart disease 44 or breast cancer 45 among women. Many studies have indicated that a high weight gain during pregnancy appears to contribute to overweight following pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Energy intake and net weight gain in pregnant women according to body mass index (BMI) status

et al. 1997

View full text Add to dashboard Cite

OBJECTIVE: To investigate whether body mass index (BMI) is related to energy intake during pregnancy, and whether BMI, energy intake and other factors are related to net weight gain. DESIGN: Longitudinal, duration of pregnancy. SUBJECTS: 156 healthy pregnant women residing in Quedlinburg county, Germany. METHODS: Weighed 7 d food records and standardized anthropometric measures in the ®rst, second and third trimester. The analysis of variance (ANOVA) statistical technique was used to analyze differences in energy intake, net weight gain and birthweight across BMI groups, and the Cochran-Mantel Haenszel test was used to analyze food group intake by BMI group. RESULTS: Women at the highest level of BMI were signi®cantly less often in the high energy intake category than women at the medium or low level of BMI (15% vs 36% and 48%). Net weight gain during pregnancy was independently in¯uenced by BMI status and energy intake. Women at the highest level of BMI gained signi®cantly less weight (4.2 kg) from ®rst to third trimester than women at the medium or low levels of BMI (weight gains of 6.2 kg and 5.9 kg, respectively). Women with a low daily energy intake gained 4.6 kg during pregnancy, while women with medium and high energy intakes gained 6.0 kg and 6.1 kg, respectively. Examination of net weight gain simultaneously across BMI and parity groups revealed a much lower net weight gain among multigravid women at the highest BMI level (3.3 kg). Primigravid high BMI women, in contrast, gained 6.9 kg, whereas multigravid and primigravid women at medium and low BMI levels gained average of 4.8 kg and 6.5 kg, respectively. The mean birth weight in the three BMI groups did not differ and was not in¯uenced by age, marital status, education, parity or smoking. CONCLUSION: Because other studies have shown that weight gain during pregnancy increases the risk of subsequent overweight, multigravid high BMI women may prevent an increased weight retention after pregnancy due to lower weight gain in the current gestation. A lower caloric diet may help to accomplish a lower weight gain during pregnancy in overweight women without increased risk of low birth weight infants. These ®ndings indicate further investigation of the associations between BMI, parity and caloric intake during pregnancy are needed to increase understanding of factors affecting subsequent weight gain.

show abstract

Section: Discussionmentioning

confidence: 99%

Energy intake and net weight gain in pregnant women according to body mass index (BMI) status

et al. 1997

View full text Add to dashboard Cite

show abstract

“…Neither Women's Health Initiative trial showed an overall protective effect of hormone therapy for coronary events, 1,2 in contrast to results of earlier observational studies. 3,4 The reasons for this discrepancy are not yet determined but may be related to differences in baseline CHD risks of the study populations and the distributions of risk factors such as lipids and hsCRP. Because clinical trials have demonstrated a small overall increase in the absolute risk of short term hormone therapy use for CHD events in postmenopausal women, we asked whether commonly utilized biomarkers (lipids and hsCRP) could be useful for predicting hormone therapy-mediated CHD risk.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of Baseline Lipids and C-Reactive Protein in Women Receiving Menopausal Hormone Therapy as Predictors of Treatment-Related Coronary Events

Bray

Larson

LaCroix

et al. 2008

The American Journal of Cardiology

View full text Add to dashboard Cite

show abstract

“…[1][2][3] Obesity and hypertension, in themselves important independent predictors of cardiovascular morbidity and mortality, 4,5 have also been identified as aetiologic factors in the development of LVH. [6][7][8][9] Obesity and hypertension often coexist in the same patient 10,11 and their joint influences on left ventricular mass (LVM) are reported to be at least additive.…”

Section: Introductionmentioning

confidence: 99%

Gender specific differences in left ventricular adaptation to obesity and hypertension

et al. 1998

View full text Add to dashboard Cite

Recent reports indicate that the prognostic implications of left ventricular hypertrophy (LVH) are more profound in women than in men. The prognosis of LVH is also related to the underlying geometric pattern. We therefore assessed the relation of separate and concurrent influences of obesity and hypertension on genderspecific patterns of LV adaptation. Five hundred and twenty participants of a community-based study (aged 52 to 67 years) were examined by M-mode echocardiography. Study subjects were divided into four groups: normals, obese, hypertensives, and subjects presenting with both obesity and hypertension. The groups were compared for various measures of left ventricular mass (LVM) and geometry. Relative to normal subjects, the increments in wall thickness, ventricle diameters, and LVM were all significant and of similar magnitude for obese men and women. Likewise, hypertensive men and

show abstract

The Primary Prevention of Coronary Heart Disease in Women

Cited by 343 publications

References 129 publications

Energy intake and net weight gain in pregnant women according to body mass index (BMI) status

Energy intake and net weight gain in pregnant women according to body mass index (BMI) status

Usefulness of Baseline Lipids and C-Reactive Protein in Women Receiving Menopausal Hormone Therapy as Predictors of Treatment-Related Coronary Events

Gender specific differences in left ventricular adaptation to obesity and hypertension

Contact Info

Product

Resources

About