The Problem of Obesity

Fitzgerald, Faith T.

doi:10.1146/annurev.me.32.020181.001253

Cited by 32 publications

(8 citation statements)

References 61 publications

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“…a failure rate at 2 years as high as 70% (9). Stunkard reported that only 25% of the patients lost 10 kg (23) and Fitzgerald reached similar conclusions in long-term studies (7). Very low calorie diets (VLCD) have been tried, but weight losses, although rapidly obtained, were seldom maintained on a long-term basis (25).…”

Section: Side Effectsmentioning

confidence: 97%

Usefulness of Fluoxetine in Obese Non‐Insulin‐Dependent Diabetics: A Multicenter Study

et al. 1996

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Weight reduction is essential in the management of most noninsulin‐dependent diabetics, but this therapeutical goal is difficult to obtain. In this double‐blind parallel study, 82 noninsulin‐dependent diabetics, moderately obese (BMI = 30–39 kg/nr2), were given for an 8‐week period either placebo (P) or fluoxetine (F), a specific serotonin reuptake inhibitor, in addition to their usual antidiabetic treatment. Thirty‐nine of them received 60 mg fluoxetine a day and 43 were given the placebo. At admission, both groups had similar weight excess, metabolic control and serum lipid values. In comparison with the P‐treated subjects, those treated with fluoxetine (F) lost more weight after 3 weeks (‐1.9 vs. −0.7 kg, p<0.0009) and after 8 weeks (‐3.1 vs. −0.9 kg, p<0.0007). Fasting blood glucose decreased in group F after 3 weeks (‐ 1.5 vs. −0.4 mmol/L, p<0.003) and after 8 weeks (‐1.7 vs. −0.02 mmol/L, p<0.0004). HbAlc decreased from 8.5% to 7.7% in group F and from 8.6% to 8.3% in group P (p=0.057). Mean triglyceride level was also reduced in group F after 8 weeks (p=0.042). Fasting C‐pep‐tide did not change in either group, but fasting insulin values decreased in group F after 3 weeks (p<0.02) and after 8 weeks (p<0.05). The insulin/C‐peptide molar ratio decreased significantly in group F after 3 weeks (p<0.04) and after 8 weeks (p<0.05) in comparison with group P. The drug was generally well tolerated and no major side effects were reported. In conclusion, the addition of fluoxetine to the usual oral hypoglycemic agent therapy might be beneficial in obese non‐insulin‐dependent diabetics, at least on a short‐term basis.

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Section: Side Effectsmentioning

confidence: 97%

Usefulness of Fluoxetine in Obese Non‐Insulin‐Dependent Diabetics: A Multicenter Study

et al. 1996

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“…In general, it would seem plausible that healthy body weights, like other physical attributes, are distributed normally in the population. Body weight appears to be homeostatically regulated around a "set point" which means that, for some, obesity is a natural and possibly healthy condition (Fitzgerald, 1981;Keesey, 1980;Nisbett, 1972). The weight history of bulimic patients not only indicates that many of them are highly prone to obesity (and probably a higher than average "set point" for body weight) but also that they have at one time lost as much body weight as found in anorexia nervosa yet they have never been emaciated.…”

Section: Unrealistic Goal Weights In Treatmentmentioning

confidence: 99%

Psychotherapy for anorexia nervosa and bulimia nervosa

Garner¹

1986

PsycEXTRA Dataset

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“…To treat simple obesity as a disease may be another matter entirely'. 25 We need to focus on the medical and emotional needs of the obese patient rather than on the size of the patient. This may help to improve the uncomfortable and potentially harmful relationships between the obese patient and the health care provider.…”

Section: Discussionmentioning

confidence: 99%

The health care disadvantages of being obese

Pryor¹

2002

NSW Public Health Bull.

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People who are obese are disadvantaged socially-in public places, in employment, and in health care. 1-2 Many obese people are afraid of approaching health professionals and attending health facilities. Problems of access and lack of suitable facilities for obese people are a problem; however, the greatest impediment is the fear of encountering judgmental and discriminatory attitudes from health professionals about a patient's obesity. Because of an increased risk of medical illnesses such as type 2 diabetes mellitus, hypertension, cardiovascular disease, stroke, sleep apnoea, gallbladder disease, and osteoarthritis, 3 the need of obese people for medical care is great. However, the recommendation of weight loss as a primary therapy may compromise and delay the management of significant medical problems. This article describes the attitude of some health professionals towards obese patients, obese patients' views about health care, myths and realties about obesity, and suggests how health care for obese patients can be improved.

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The Problem of Obesity

Cited by 32 publications

References 61 publications

Usefulness of Fluoxetine in Obese Non‐Insulin‐Dependent Diabetics: A Multicenter Study

Usefulness of Fluoxetine in Obese Non‐Insulin‐Dependent Diabetics: A Multicenter Study

Psychotherapy for anorexia nervosa and bulimia nervosa

The health care disadvantages of being obese

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