Mine activities may cause serious environmental problems. Whether the solid wastes from the mine pollute the environment is the one of the problems. The solid wastes from the Nanjing YinMao Lead-Zinc Mine were investigated by multiple mineralogical techniques in this paper. Calcite and quartz were the major components of the solid wastes by X-ray diffraction spectrum. Several elements such as O, Mg, Zn, Fe, Mn, Ca, K, S, Si, Al, As and Na were detected in the solid wastes by electron microprobe analysis. Although the solid wastes contained heavy metals, their concentrations in the leaching solution of the solid wastes by ICP were less than the identification standard for hazardous waste. Therefore, the solid wastes from the Nanjing YinMao Lead-Zinc Mine are not hazardous.