The prognosis of agenesis of the corpus callosum might mostly be favourable

Visual System Abnormalities in a Case of Nonsyndromic, Complete, Isolated Corpus Callosum Agenesis

“…Regarding the observed ocular motility deficits (pendular nystagmus and ocular muscles hypofunctions), we agree with the already reported finding in isolated CCA (3). For instance, Ramelli et al (3) observed one case of pendular nystagmus in a cohort of 6 CCA-affected children.…”

“…Regarding the observed ocular motility deficits (pendular nystagmus and ocular muscles hypofunctions), we agree with the already reported finding in isolated CCA (3). For instance, Ramelli et al (3) observed one case of pendular nystagmus in a cohort of 6 CCA-affected children. Pendular nystagmus, rarely seen associated to CCA, is usually observed in demyelinating disorders and other deficits, such as pharmacological intoxication, metabolic, genetic, and granulomatous disorders.…”

“…When a CCA occurs in a syndromic condition, due to chromosomal anomalies (2), relevant ocular findings are marked optic nerve pallor, optic nerve hypoplasia, or chiasmal defects (1). In the isolated condition, minimal ocular findings have been reported (3).…”