The Prognostic Value and Significance of Serial Bone Scintigraphy in Legg-Calvé-Perthes Disease

Tsao, Audrey K.; Dias, Luciano; Conway, James J.; Straka, P

doi:10.1097/01241398-199703000-00018

Cited by 33 publications

(24 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Good prognosis was found to correlate with the described pathway A, and poorer prognosis was found to correlate with pathways B and C. 71 The limitations of serial bone scan entailed radiation exposure, cost, and quality of the image. Good prognosis was found to correlate with the described pathway A, and poorer prognosis was found to correlate with pathways B and C. 71 The limitations of serial bone scan entailed radiation exposure, cost, and quality of the image.…”

Section: Serial Bone Scintigraphy 71mentioning

confidence: 95%

Prognosis and Prognostic Factors of Legg-Calve-Perthes Disease

Cheng

Lam

2011

Journal of Pediatric Orthopaedics

View full text Add to dashboard Cite

This is an overall review of the published literature in the past 100 years on the prognosis and prognostic factors of Legg-Calve-Perthes disease (LCPD). There were considerable limitations and inadequacies of the reported series. LCPD is not a common disease, and thus most reports were based on relatively small series collected retrospectively over a long period of time without clearly defined case selection, assessment, treatment, follow-up period, and outcome measures. Few studies, if any, would satisfy the strict definition of prognosis, which should only mean those prognostic factors derived from observation of the natural history of the disease-that is the uninterrupted progressive development of a disease that runs its course from onset-inception to resolution without any intervention or treatment. This review attempted to summarize from the mixed series of studies the generally described demographic, clinical, and radiologic prognostic factors of LCPD. The most important radiologic prognostic signs include the extent of femoral capital epiphysis involvement, the degree of metaphyseal changes, and lateral subluxation of femoral head and depend significantly on the time of assessment after the onset of the disease. More detailed discussions on prognostication based on the structured classification systems that have evolved in the past few decades would be described.

show abstract

Section: Serial Bone Scintigraphy 71mentioning

confidence: 95%

Prognosis and Prognostic Factors of Legg-Calve-Perthes Disease

Cheng

Lam

2011

Journal of Pediatric Orthopaedics

View full text Add to dashboard Cite

show abstract

“…The appearance of Perthes' disease on bone scan has been demonstrated to be characteristic with a marked void in activity in the femoral epiphysis at a very early stage, and signs of revascularisation have been demonstrated later in the course of the disease (Danigelis 1975, 1976, Sutherland et al 1980, Calver 1981. With bone scan, it is possible to classify Perthes' disease into stages of revascularisation (Tachdjian 1984, Tsao et al 1997, and serial bone scan have been shown to have prognostic significance regarding later femoral head involvement and degree of deformity at healing (Tsao et al 1997). However, bone scan lacks the ability to describe the shape of the femoral head and its relationship with the acetabulum.…”

Section: Other Imaging Methodsmentioning

confidence: 99%

Perthes' disease in Norway

Wiig

2009

Acta Orthopaedica

View full text Add to dashboard Cite

“…Conway's group demonstrated the prognostic value of bone scintigraphy. 34,35 They found that the persistent absence of bone uptake in the proximal femoral epiphysis after 5 months or metaphyseal hyperactivity is highly correlated with more severe disease and a poorer prognosis. The early formation of a lateral column of tracer uptake in the capital femoral epiphysis, even before radiography, is associated with a good prognosis due to early revascularization.…”

Section: Septic Arthritis and Transient Synovitismentioning

confidence: 99%

Nuclear Medicine Imaging of the Pediatric Musculoskeletal System

Shammas

2009

Semin Musculoskelet Radiol

View full text Add to dashboard Cite

Bone scintigraphy is a common pediatric nuclear medicine procedure and plays a significant role in the diagnosis of skeletal infection, trauma, and benign and malignant bone tumors. There is a complementary role for bone scintigraphy in the assessment of a child with suspected nonaccidental injury. High-quality images require careful attention to technique and positioning in children. Additional techniques such as magnification and single-photon emission computed tomography (SPECT) can be used for special indications and localization. Combined functional and anatomic imaging using SPECT/computed tomography (CT) imaging systems can improve diagnostic accuracy. Positron emission tomography (PET) using fluorine-18 fluorodeoxyglucose (FDG) is being applied with increasing frequency in the evaluation of children with malignancy. To interpret (18)F-FDG PET appropriately, it is essential to know the normal physiological distribution. Using combined (18)F-FDG PET/CT improves specificity and localization. This article reviews the common indications for bone scintigraphy and (18)F-FDG PET/CT in benign and malignant pediatric musculoskeletal disease.

show abstract

The Prognostic Value and Significance of Serial Bone Scintigraphy in Legg-Calvé-Perthes Disease

Cited by 33 publications

References 50 publications

Prognosis and Prognostic Factors of Legg-Calve-Perthes Disease

Prognosis and Prognostic Factors of Legg-Calve-Perthes Disease

Perthes' disease in Norway

Nuclear Medicine Imaging of the Pediatric Musculoskeletal System

Contact Info

Product

Resources

About