The Prognostic Value of Residual Nonrectal Inflammation in Ulcerative Colitis

Abstract

2 www.gutnliver.org maintained CR status because the patients used highly effective medications such as immunomodulators or biologics. 9,10 Therefore, the possibility of bias cannot be ruled out.Third, Supplementary Fig. 1 shows the changes in the distribution of residual inflammation according to the distribution of inflammation in UC patients in CR. However, the figure fails to show if clinical outcomes differed according to the change of distribution: from rectal inflammation (n=51) to endoscopic remission (n=16), nonrectal inflammation (n=2), or sustained rectal inflammation (n=33).In conclusion, as the authors noted, well-designed prospective studies are needed to support the findings of this study. With stronger evidence, customized treatment according to a patient's residual rectal inflammation status will be possible. CONFLICTS OF INTERESTNo potential conflict of interest relevant to this article was reported.