The Progress in Bioprinting and Its Potential Impact on Health-Related Quality of Life

Abstract

The intensive development of technologies related to human health in recent years has caused a real revolution. The transition from conventional medicine to personalized medicine, largely driven by bioprinting, is expected to have a significant positive impact on a patient’s quality of life. This article aims to conduct a systematic review of bioprinting’s potential impact on health-related quality of life. A literature search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive literature search was undertaken using the PubMed, Scopus, Google Scholar, and ScienceDirect databases between 2019 and 2023. We have identified some of the most significant potential benefits of bioprinting to improve the patient’s quality of life: personalized part production; saving millions of lives; reducing rejection risks after transplantation; accelerating the process of skin tissue regeneration; homocellular tissue model generation; precise fabrication process with accurate specifications; and eliminating the need for organs donor, and thus reducing patient waiting time. In addition, these advances in bioprinting have the potential to greatly benefit cancer treatment and other research, offering medical solutions tailored to each individual patient that could increase the patient’s chance of survival and significantly improve their overall well-being. Although some of these advancements are still in the research stage, the encouraging results from scientific studies suggest that they are on the verge of being integrated into personalized patient treatment. The progress in bioprinting has the power to revolutionize medicine and healthcare, promising to have a profound impact on improving the quality of life and potentially transforming the field of medicine and healthcare.

Three-dimensional printed models can reduce costs and surgical time for complex proximal humeral fractures: preoperative planning, patient satisfaction, and improved resident skills

“…Personalized medicine in surgery represents a continuous search for improvement, reducing risks and human errors [ 21 , 22 ]. As a result of the revolutionary changes in orthopedic and trauma diagnoses brought about by the discovery of X-rays in 1895, as of now, digital technologies and 3D printing are so widespread and well-liked that they are widely used in both trauma and arthroplasty [ 23 , 24 ]. The main findings of this paper are that a 3D replica of a PHF can assist surgeons in diagnosing, planning, and performing ORIF, increase patient compliance, and improve residents’ satisfaction.…”

“…Scientific attention toward the use of 3D-printed replicas has increased a lot in recent years, however the application in the daily routine of this technology for traumatic joint bone injuries is less widespread and common [ 7 , 23 ]. This discrepancy may be due to difficulties in organizing the workflow of 3D printing organizations (emergency, radiologic, and orthopedic departments), as well as the availability of equipment and resources [ 18 ].…”

(3D) Bioprinting—Next Dimension of the Pharmaceutical Sector

“…With the growing interest in cosmetic/aesthetic strategies and increasing rates of weight, diabetes, and a maturing population, the recovery of damaged or lost tissue has become a global issue, and the demand for skin biomanufacturing is continuously increasing. It is suggested that bioprinted skin allows for an elective approach to clinical applications in regenerative medication (inveterate wounds, burns, ulcerations, reconstructive surgery after major oncological resections); the modeling of physiological/pathological conditions (wound healing, UV reactions, aging, skin layer penetrability, drug reactions, photoirradiation, skin cancer, genodermatoses, burn conditions); and in the cosmetic/pharmaceutical industry (safety and efficacy of active substances, drug retention, drug metabolism, personalized treatments) [ 103 ]. Moreover, bioprinted skin models can serve as a platform for creating modern drug formulations [ 77 ].…”

Data Analysis of Biomechanical Dynamic Modeling of a Prosthetic Running Blade

“…Biomechanics has long been integral to developing and refining prosthetic devices, focusing on the dynamic interactions between the human body and prosthetic components (Savin et al, 2023;Yaneva et al, 2023). In prosthetic running blades, explicit dynamic modeling emerges as a pivotal tool, enabling a deeper understanding of the complex biomechanical interactions.…”