The Promise and Limitations of TNF-α Inhibition for Uveitis

The Creeping Choroiditides – Serpiginous and Multifocal Serpiginoid Choroiditis

“…Others [18][19][20] have reported the use of anti-TNF-a agents, including adalimumab, 15 to treat SC, supporting the broad utility of TNF-a inhibitors in patients with noninfectious uveitis. 21,22 Together, these four studies highlight important features of SC and MSC, including the utility of both multimodal imaging and ancillary testing; the frequent need for non-corticosteroid immunosuppressive therapy; 23 and the importance of excluding systemic infection in patients with placoid lesions involving the outer retina and inner choroid -most notably infection by M. tuberculosis.…”