Commons scholarship has improved our understanding of how to govern resources for sustainability. However, it has also been critiqued for its focus on traits that are increasingly threatened by social and environmental trends. Fisheries are a key example of this challenge. While small-scale fisheries are critically important to the diets and livelihoods of millions, industrial fisheries now dominate fishing around the world. While these two systems are governed separately, there is substantial overlap between them, conceptualized as the growing influence of globalization on local common pool resource (CPR) systems. One of the most impactful, but least understood consequences of this convergence are the conflicts and competition between small-scale and industrial fisheries. We use empirical data from 396 cases of interactions at sea between globalized industrial and local small-scale fishers in Ghana from 1984-2013 to examine the conditions under which resource users conflict or cooperate, linking them to broader political and economic dynamics across scales. We consider the institutional factors that mediate these interactions, identifying policies to promote cooperative, and avert conflictual incidents. We further consider the long-term effects of these patterns of conflict and cooperation for the resilience or vulnerability of the resource system as a whole. We suggest that specific governance arrangements that reduce disparities between groups, promote bridging social capital, and enhance hybrid and cross-scale institutions offer the best potential to govern resource systems where traditional CPRs and market-oriented industries converge.