The prophylactic effect of vitamin C supplementation on broiler ascites incidence and plasma thyroid hormone concentration

Ladmakhi, MH; Buys, Nadine; Dewil, Erna; Rahimi, G; Decuypere, Eddy

doi:10.1080/03079459708419191

Cited by 49 publications

(14 citation statements)

References 24 publications

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“…The results of the present study demonstrate that the administration of AA just before journey start is beneficial in terms of reducing the stressful effect of being transported during hot and humid weather. In addition, they confirm previous findings that AA increases body resistance to environmental stress [12,22,23], by altering the hormones or factors responsible for a shift in the homeostatic mechanism during stressful conditions [18], and by so doing restores the organism's excitability.…”

Section: Discussionsupporting

confidence: 87%

Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions

2006

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In this study, we investigated the effect of ascorbic acid (AA) administration on goat excitability due to transportation. Ten goats administered AA (p.o.) at 100 mg/kg of body weight before transportation served as the experimental group, and seven goats administered only 10ml/kg of sterile water (p.o.) served as controls. Excitability scores were recorded for each goat; when weighed, before, immediately after, and 3 h after 8 h of transportation. A score of one to four was allocated to each goat; higher scores represent greater excitability. Immediately after transportation, excitability scores decreased significantly, especially those of control goats (p < 0.001). At 3 h post-transportation, the excitability scores of animals in the experimental group were not significantly (p>0.05) different from their pre-transportation normal values, whereas those of control goats were significantly lower (p < 0.01). The correlation i.e. the relationship between excitability score values and percent excitability (percentage of goat with particular excitability score) for different excitability score group 3 h post-transportation was positive and highly significant (p < 0.001), in both experimental and control goats. Our results indicate that road transportation induces considerable stress (depression) in goats as evidenced by a lower excitability score post-transportation. Moreover, the administration of AA pre-transportation facilitated the transition from a state of depression to excitation. In conclusion, AA administration to animals prior to transportation may ameliorate the depression often encountered after road transportation.

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Section: Discussionsupporting

confidence: 87%

Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions

2006

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“…(2005) reported similar results. However, Ladmakhi et al. (1997) showed that AA up to 500 ppm had no effect on F:G of broilers maintained in the cyclic temperature (24–35 °C) during 28–42 days of age.…”

Section: Discussionmentioning

confidence: 94%

Effect of ascorbic acid or increasing metabolizable energy level with or without supplementation of some essential amino acids on productive and physiological traits of slow‐growing chicks exposed to chronic heat stress

Attia

Hassan

El-Din

et al. 2010

Animal Physiology Nutrition

104

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Four hundred and twenty, 21-day-old slow-growing chicks were divided randomly into seven treatments, each containing five replicates. Each replicate was kept in a 1 × 1-m floor pen. One treatment was kept under thermo-neutral conditions in a semi-open house and fed a corn-soybean meal diet (positive control). The other six groups were kept under chronic heat stress (CHS) at 38 °C and 60% RH for 4 h from 12:00 to 16:00 pm for three successive days per week. Chicks in CHS treatments were fed a corn-soybean meal diet without (negative control) or with increasing metabolizable energy (ME) level by oil supplementation alone, or also with increasing some essential amino acids (EAA) such as methionine (Met), methionine and lysine (Met+Lys) or methionine, lysine and arginine (Met+Lys+Arg) or supplemented with 250 mg of ascorbic acid (AA)/kg. CHS impaired (p < 0.05) growth performance, increased plasma triglycerides and total serum Ca while decreasing (p < 0.05) plasma glucose and total serum protein. Meanwhile 250 mg AA/kg diet or an increasing ME without or with some EAA partially alleviated (p < 0.0001) the negative effect of CHS on growth while increasing (p < 0.05) feed intake and improving (p < 0.05) feed:gain ratio (F:G) and crude protein (CP) digestibility (p < 0.05). AA or increasing ME with or without EAA increased (p < 0.05) percentage dressing, liver and giblets to those of the positive control. AA or increasing ME with or without EAA partially alleviated the negative effect of CHS on blood pH, packed cell volume (PCV), haemoglobin (Hgb), total serum protein and total Ca, plasma glucose and triglyceride, rectal temperature and respiration rate. Increasing ME level improved chickens' tolerance to CHS without a significant difference from those supplemented with AA. However, increasing Met, Lys and Arg concentration did not improve performance over that recorded with increasing ME level alone. Under CHS, 250 mg AA/kg diet or increasing ME level by addition of 3% vegetable oil could be an useful approach to improve productive and physiological traits of slow-growing chicks, which may be applicable also to fast-growing one.

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“…Nevertheless, Packed Cell Volume, weight gain and feed efficiency were not affected by the treatment (Table 1). In addition to the suggestions that vitamin C may exert positive effects on alleviating ascites because it depresses the oxygen-derived free radical status (Ladmakhi et al, 1997), the results presented in Table 1 show that vitamin C markedly reduced the muscularization of the pulmonary arterioles as indicated by the lower number of thick-walled peripheral vessels (TWPV). Thus, it may reduce the resistance to blood flow that is seen in pulmonary vessels of broilers.…”

Section: Nutritional Controlmentioning

confidence: 92%

Strategies to alleviate the incidence of ascites in broilers: a review

Aftab

Khan

2005

Rev. Bras. Cienc. Avic.

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Ascites is a complex problem caused by many interacting factors such as genetics, environment and management. Many nutritional, medicinal and management strategies have been proposed to alleviate the problem. Higher levels of dietary vitamin C and E along with selenium yeast might be beneficial, presumably because of their role in improving cellular integrity. Oils rich in n-3 fatty acids have been shown to reduce pulmonary hypertension and, consequently, ascites incidence. The potential use of flax oil has already been demonstrated, whereas the effects of other oils rich in n-3 fatty acids (fish, linseed and canola oils) remain to be investigated. The assessment of the effects of dietary electrolyte balance on ascites incidence seems to be a promising field of research in broiler nutrition. In general, reducing the dietary level of salt (NaCl) and adding bicarbonates to the diet and drinking water have been proposed as potential "cost-effective" methods to reduce ascites incidence. The use of nutrients/drug agents that increase the vascular capacity of the lungs or decrease the pulmonary vascular resistance may help to alleviate the problem, but economic and local feed regulations might restrict such use. Diuretics have also shown positive effects, presumably because there is a reduction of sodium and fluid retention in the body; litter humidity however must be closely monitored if diuretics are continuously administered. As the high metabolic rate (fast growth) is a major factor contributing to the susceptibility of broilers to ascites, early-age feed or nutrient restriction (qualitative or quantitative) or light restriction in order to slow down the growth rate seem practically viable methods, since final body weight is not compromised. Optimization of the house temperature and ventilation in cold weather seem helpful practices to decrease ascites incidence. Under practical conditions, it might be interesting to test the additive effects of different approaches when used in combination

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The prophylactic effect of vitamin C supplementation on broiler ascites incidence and plasma thyroid hormone concentration

Cited by 49 publications

References 24 publications

Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions

Excitability scores of goats administered ascorbic acid and transported during hot-dry conditions

Effect of ascorbic acid or increasing metabolizable energy level with or without supplementation of some essential amino acids on productive and physiological traits of slow‐growing chicks exposed to chronic heat stress

Strategies to alleviate the incidence of ascites in broilers: a review

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