2020
DOI: 10.1111/aas.13540
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The prophylactic use of fibrinogen concentrate in high‐risk cardiac surgery

Abstract: Background Perioperative blood loss is a major contributor to morbidity and mortality in cardiac surgery. Plasma fibrinogen levels play an essential role in hemostasis and deplete quickly during hemorrhage. The objective of this study was to determine whether prophylactic fibrinogen concentrate administration lowers overall blood product transfusion requirements in high‐risk cardiac surgery in patients with low fibrinogen plasma levels. Methods The study was performed in a prospective, randomized, and double‐b… Show more

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Cited by 6 publications
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