2017
DOI: 10.2147/opth.s120159
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The Prospective Health Assessment of Cataract Patients’ Ocular Surface (PHACO) study: the effect of dry eye

Abstract: PurposeTo determine the incidence and severity of dry eye as determined by the International Task Force (ITF) scale in patients being screened for cataract surgery.Patients and methodsThis was a prospective, multi-center, observational study of 136 patients, at least 55 years of age, who were scheduled to undergo cataract surgery. The primary outcome measure was the incidence of dry eye as evaluated by grade on the ITF scale and secondary outcome measures include tear break-up time (TBUT), ocular surface disea… Show more

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Cited by 98 publications
(85 citation statements)
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“…The situation is further complicated as pre-existing DED in patients with cataracts is frequent, 17 , 18 with one study in a prospective series of 120 patients presenting with cataracts, reporting that 80% had at least 1 abnormal test indicative of ocular surface disease (OSD) prior to surgery. 17 These findings are in keeping with those of a multi-centre prospective study of 136 patients which revealed that 77% had positive corneal staining and 63% TBUTs of less than 5 seconds prior to cataract surgery.…”
Section: Prevalence Of Cataract Surgery Associated Dedmentioning
confidence: 99%
See 1 more Smart Citation
“…The situation is further complicated as pre-existing DED in patients with cataracts is frequent, 17 , 18 with one study in a prospective series of 120 patients presenting with cataracts, reporting that 80% had at least 1 abnormal test indicative of ocular surface disease (OSD) prior to surgery. 17 These findings are in keeping with those of a multi-centre prospective study of 136 patients which revealed that 77% had positive corneal staining and 63% TBUTs of less than 5 seconds prior to cataract surgery.…”
Section: Prevalence Of Cataract Surgery Associated Dedmentioning
confidence: 99%
“… 17 These findings are in keeping with those of a multi-centre prospective study of 136 patients which revealed that 77% had positive corneal staining and 63% TBUTs of less than 5 seconds prior to cataract surgery. 18 …”
Section: Prevalence Of Cataract Surgery Associated Dedmentioning
confidence: 99%
“…In this observational study, it is found that about 77% of the eyes have positive corneal staining, 60% have tear film break up time of ≤ 5 seconds, and 21% have Schirmer's scores of ≤ 5 mm. The majority of patients didn't report symptoms that are suggestive of dry eye [1].…”
Section: Introductionmentioning
confidence: 99%
“…15 – 17 But the PHACO study found closer to 60% of patients undergoing screening for routine cataract surgery had rapid tear breakup time (TBUT) and approximately 50% had central corneal staining, both of which are hallmarks of DED. 18 …”
Section: Introductionmentioning
confidence: 99%
“…25 – 30 Corneal staining, one of the cardinal signs of DED that is known to reduce the accuracy of keratometry readings, was improved significantly after 4 weeks of treatment in the FDA registration trial of lifitegrast, so it seems an appropriate treatment choice for preparing eyes for cataract surgery biometry. 18 , 27 , 28 , 31 In this study, we sought to determine if the refractive accuracy of anterior corneal power readings is improved when lifitegrast is administered preoperatively to patients who are scheduled for cataract surgery and who have confirmed DED (defined here as a TBUT ≤ 10 seconds and central or inferior corneal staining as defined by the Oxford Scale).…”
Section: Introductionmentioning
confidence: 99%