The Protean Face of Renal Sarcoidosis

Göbel, U; Kettritz, Ralph; Schneider, Wolfgang; Luft, Friedrich C.

doi:10.1681/asn.v123616

Cited by 72 publications

(2 citation statements)

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“…Renal sarcoid granulomas can be found in both cortical and medullary compartments. Sarcoid nodules can sometimes reach a diameter of 1 cm, thus becoming difficult to differentiate from neoplastic lesions [ 64 ].…”

Section: Clinical Pictures Of Sarcoidosismentioning

confidence: 99%

“…Acute and clinically overt renal failure that leads to hemodialysis is uncommon and derives most frequently from an acute granulomatous tubulointerstitial nephritis [ 63 ]. Glomerular involvement in sarcoidosis is not common and the mechanism of glomerular damage is not completely known; an autoimmune etiology has been hypothesized because some patients with sarcoidosis and crescent glomerulonephritis or glomerular interstitial nephropathy are positive for antibodies directed against the cytoplasm of neutrophils [ 64 ].…”

Section: Clinical Pictures Of Sarcoidosismentioning

confidence: 99%

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Clinical Features, Histopathology and Differential Diagnosis of Sarcoidosis

Tana

Donatiello

Caputo

et al. 2021

Cells

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Sarcoidosis is a chameleon disease of unknown etiology, characterized by the growth of non-necrotizing and non-caseating granulomas and manifesting with clinical pictures that vary on the basis of the organs that are mainly affected. Lungs and intrathoracic lymph nodes are the sites that are most often involved, but virtually no organ is spared from this disease. Histopathology is distinctive but not pathognomonic, since the findings can be found also in other granulomatous disorders. The knowledge of these findings is important because it could be helpful to differentiate sarcoidosis from the other granulomatous-related diseases. This review aims at illustrating the main clinical and histopathological findings that could help clinicians in their routine clinical practice.

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Section: Clinical Pictures Of Sarcoidosismentioning

confidence: 99%

Section: Clinical Pictures Of Sarcoidosismentioning

confidence: 99%