The protean manifestations of mycoplasma pneumoniae infection in adults

Murray, Henry W.; Masur, Henry; Senterfit, Laurence B.; Roberts, Richard B.

doi:10.1016/0002-9343(75)90574-4

Cited by 249 publications

(55 citation statements)

References 80 publications

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“…Against the diagnosis was the dense nature of the focal/ segmental pulmonary infiltrate, the CAP severity, a temperature greater than 102°F, and the absence of highly elevated cold agglutinin titers. 1,[10][11][12][13][14][15][16] Patients with M. pneumoniae and meningoencephalitis have …”

Section: Discussionmentioning

confidence: 99%

C. pneumoniae community-acquired pneumonia (CAP) in mimicking Mycoplasma pneumoniae meningoencephalitis complicated by asthma

Cunha

Pherez²

2009

Heart & Lung

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Section: Discussionmentioning

confidence: 99%

C. pneumoniae community-acquired pneumonia (CAP) in mimicking Mycoplasma pneumoniae meningoencephalitis complicated by asthma

Cunha

Pherez²

2009

Heart & Lung

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“…The more usual hematological complication of M. pneumoniae infection is hemolysis, occurring 2–3 weeks after the onset of symptoms [21]. In view of our better understanding of the association between decreased plasma activity of the vWf-cleav…”

Section: Discussionmentioning

confidence: 99%

<i>Mycoplasma-pneumoniae</i>-Induced Thrombotic Thrombocytopenic Purpura

Meir¹,

Amital²,

Levy³

et al. 2000

Acta Haematol

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Thrombotic thrombocytopenic purpura (TTP) is a fatal disease characterized by widespread platelet aggregation, hemolytic anemia and fever with renal and neurological involvement. Different factors have been associated with the development of TTP, e.g. infections, pregnancy, chemotherapy, drug therapy and bone marrow transplantation. Recent data imply that all these different causes may induce the disease by decreasing the activity of the plasma von Willebrand factor-cleaving protease resulting in unusually large von Willbrand factor multimers that later on initiate the cascade of TTP. In this communication, we present a unique association between infection with Mycoplasma pneumoniae and TTP. We believe that the emergence of antibodies that cross-react with Mycoplasma and the protease might elucidate in this case the pathogenesis of TTP.

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“…Although Mycoplasma pneumoniae infection usually affects the respiratory tract in older children and young adults, extrapulmonary involvement may also occur, including hematopoietic, cardiovascular, central nervous, musculoskeletal, cutaneous, gastrointestinal, hepatobiliary, genitourinary system, and occasionally multiorgan disease [1,2]. Among these, simultaneous elevations of liver enzymes associated with M. pneumoniae infection have been reported to occur in 50% of patients with M. pneumoniae -induced pneumonia [3].…”

Section: Introductionmentioning

confidence: 99%

Clinical Characteristics of Patients with Mycoplasma pneumoniae-Related Acute Hepatitis

Shin¹,

Park²,

Kim³

et al. 2012

Digestion

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Background/Aims: Although the hepatobiliary manifestations of Mycoplasma pneumoniae infection have been described in several previous studies, controversies still remain. The aim of this study was to evaluate the clinical characteristics of patients with M. pneumoniae-related hepatitis and compare to those with M. pneumoniae infection but not hepatitis. Methods: We reviewed the medical chart of patients diagnosed with M. pneumoniae infection serologically. Results: Among the 117 patients with M. pneumoniae infection enrolled in the study, 25 showed acute hepatitis without any evidence of another cause. Patients with hepatitis presented with prodromal symptoms more frequently and also had a higher body temperature and C-reactive protein (CRP) levels than patients without hepatitis. Frequencies of respiratory tract involvement were not different between two groups. Clinical signs recovered within three weeks in both groups following the institution of antibiotic therapy. Multivariate analysis revealed that male sex, age <40 years, and high CRP levels were significantly linked to M. pneumoniae-related hepatitis. Conclusions: We found that acute hepatitis associated with M. pneumoniae occurred in about 21% of all M. pneumoniae infections, and gender, age, and CRP levels were factors related to the occurrence of M. pneumoniae-related hepatitis.

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The protean manifestations of mycoplasma pneumoniae infection in adults

Cited by 249 publications

References 80 publications

C. pneumoniae community-acquired pneumonia (CAP) in mimicking Mycoplasma pneumoniae meningoencephalitis complicated by asthma

C. pneumoniae community-acquired pneumonia (CAP) in mimicking Mycoplasma pneumoniae meningoencephalitis complicated by asthma

<i>Mycoplasma-pneumoniae</i>-Induced Thrombotic Thrombocytopenic Purpura

Clinical Characteristics of Patients with Mycoplasma pneumoniae-Related Acute Hepatitis

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