Lipopolysaccharide (LPS) from the Escherichia coli serotype 0111:B4 at concentrations of 0.1 and 0.125 mg/ml was shown to exert an apoptotic effect on the neuronal PC12 cell line in DMEM (serum free medium). Gangliosides GD1a and GM1 at a concentration of 100 μM were found to raise the PC12 cell line viability and decrease the percentage of PC12 cells in the late-phase apoptosis after exposure to LPS. GD1a and GM1, antiapoptotic effect, flow cytometry. thereby the bacterial LPS-induced DNA fragmentation. Such compounds as, for example, the triazide and oxazine derivatives, are synthesized by pharmacologists [6,7]; among the natural protectors, most studied are flavonoids, for example,