The protective effect of Lactobacillus and Bifidobacterium as the gut microbiota members against chronic urticaria

Gut Microbiome and Serum Metabolome Analyses Identify Unsaturated Fatty Acids and Butanoate Metabolism Induced by Gut Microbiota in Patients With Chronic Spontaneous Urticaria

“…At the phylum level, when compared with healthy controls, there was a relative reduced abundance of Bacteroidetes and Firmicutes in CSU patients, which is partly in agreement with the airway allergies in young children (Chiu et al, 2019). At the genus level, members of the Bacteroides, Faecalibacterium, Bifidobacterium, Lactobacillus, and unidentified Ruminococcaceae were relatively lower and members of unidentified Enterobacteriaceae were relatively increased compared to healthy controls, which is partly consistent with previous studies about CU or allergic diseases (Sjogren et al, 2009;Johansson et al, 2011;Candela et al, 2012;Nabizadeh et al, 2017;Rezazadeh et al, 2018;Chiu et al, 2019). For example, Nabizadeh et al (2017) and Rezazadeh et al (2018) reported a depletion in the relative amounts of Faecalibacterium prausnitzii, Clostridia, Akkermansia muciniphila, Bifidobacterium, and Lactobacillus in CU patients.…”

“…We previously conducted an epidemiologic investigation and found relevant evidence linking gut microbiota and CSU. Several studies have suggested that the changes in gut microbiota composition are linked to CU, including Akkermansia muciniphila, Faecalibacterium prausnitzii, the Clostridium leptum group, the Enterobacteriaceae family (Nabizadeh et al, 2017), and the Lactobacillus, Bifidobacterium, and Bacteroides genera (Rezazadeh et al, 2018); however, there is no specific mechanism by which to explore the dysbiosis of gut microbiota in the pathogenesis of CSU.…”

Probiotic as an adjuvant therapy in chronic urticaria: a blinded randomized controlled clinical trial

“…In addition, this review emphasis on further research to evaluate how probiotics and prebiotics could be better used in dermatology. In a study by Rezazadehet al, (35) from Iran, authors investigated the protective effect of Lactobacillus and Bifidobacterium against chronic urticaria. In this study, stool samples of 20 patients with chronic urticaria were compared with 20 age-and sex-matched healthy controls in terms of Lactobacillus, Bifidobacterium and Bacteroides contents.…”

Luteolin, inflammation and cancer: Special emphasis on gut microbiota

“…40 Overall, the presence of these two strands has been linked to better health in general, with a reduction of mood disorders 41 and other conditions. 42,43 Overall, it appears that microbiota modulation impacts inflammation in the organism. In Table 1, the effect of consumption of luteolin and other flavonoids on microbiota composition are described.…”

“…Bifidobacterium has also been associated to a reduced incidence of obesity, while Lactobacillus seems to reduce the severity of inflammatory bowel disease (IBD) 40 . Overall, the presence of these two strands has been linked to better health in general, with a reduction of mood disorders 41 and other conditions 42,43 . Overall, it appears that microbiota modulation impacts inflammation in the organism.…”