2019
DOI: 10.22159/ijcpr.2019v11i5.35713
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The Protective Effect of the Carthmus Tinctorius Leaves Extracton Methotrexate-Induced Pulmonary Fibrosis in Rats

Abstract: Objective: Pulmonary fibrosis (PF) is an irreversible and untreatable human disease encompasses a large group of chronic lung disorders associated with excessive remodeling, scarring, and fibrosis.The current work was designed to study the harmful effects of methotrexate (MTX) administration on the lung and the possible protective role of Carthmus tinctorius leaves extract. The animals were utilized in this study. Methods:A total of 40 male healthy adult Wistar albino rats with anaverage body weight of 200±25 … Show more

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