1979
DOI: 10.1016/0010-7824(79)90082-9
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The protective influence of progestogen only contraception against vaginal moniliasis

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1986
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Cited by 15 publications
(9 citation statements)
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“…Conversely, it is known that a hypoestrogenic state such as that induced by the use of depomedroxyprogesterone can lead to a loss of epithelial glycogen and a marked reduction in Candida. 15,23 We did not see a significant increase in the percentage of women with yeast by culture, but we did see a nonsignificant increase in the estimated average concentrations of yeast with pill use (P ϭ .08). Perhaps the oral contraceptive with enterohepatic circulation stimulates vaginal glycogen production more than vaginal absorption of an estrogen?…”
Section: Discussioncontrasting
confidence: 52%
“…Conversely, it is known that a hypoestrogenic state such as that induced by the use of depomedroxyprogesterone can lead to a loss of epithelial glycogen and a marked reduction in Candida. 15,23 We did not see a significant increase in the percentage of women with yeast by culture, but we did see a nonsignificant increase in the estimated average concentrations of yeast with pill use (P ϭ .08). Perhaps the oral contraceptive with enterohepatic circulation stimulates vaginal glycogen production more than vaginal absorption of an estrogen?…”
Section: Discussioncontrasting
confidence: 52%
“…49 In 1979, a study by Toppozada et al suggested that those using DMPA had reduced incidence of candidal vaginal cultures compared with those not using it, and the incidence of vaginal candidiasis reduced even further with long-term users. 50 The use of DMPA with recurrent VVC has not been published in an RCT. Dennerstein's interest in this area resulted in an observational study that followed a group of 15 women with recurrent VVC who used DMPA for contraception for up to seven years.…”
Section: History Of Allergiesmentioning
confidence: 99%
“…It is also less than that of Depot medroxyprogesterone acetate (150mg per 3 months) and Norethisterone enanthate (200rag per 3 months) [14]. This low progestogen level among Norplant users will probably not affect the glycogen content of the vaginal epithelium nor will it cause its increase.…”
Section: Discussionmentioning
confidence: 88%
“…The probability that the observed increase in CA at 6 months is not related to the Norplant progestogen itself is further supported by the fact that progestogenonly injectable contraceptives are associated with a decrease in the incidence of vaginal candidiasis [14].…”
Section: Discussionmentioning
confidence: 95%