The Protective Role of Curcumin and Melatonin in Amelioration of Cadmium- Induced Cardiac Toxicity in Adult Albino Rats

Eldin, Hoda Salah; Hafez, Rabab

doi:10.21608/ajfm.2016.18553

Cited by 1 publication

(1 citation statement)

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“…This assertion is so because the CTP1 has been identified as a superior marker for the left ventricular malfunction (Buiten et al 2015) and that in most cases, wherever there is a rise in CTP, it is indicative of heart damage or a very recent myocardial infarction. Our findings therefore agree with previous studies of Salah and Hafez (2016), which reported increased CTPI levels in rats exposed to CdCl2 in an oxidative cardiac toxicity model. It also further supports Liu et al, (2021) which observed an elevation of cardiac troponin in mice exposed to cadmium.…”

Section: Resultssupporting

confidence: 93%

Single and Combined Aluminium and Cadmium Exposure during Pregnancy Mediate Changes in Cardio Metabolic Indices in Mice

Onavwose,

Ichipi-Ifukor,

Asagba

2024

jasem

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The potential risk of Aluminium and Cadmium co-exposure is high owing to evidence of their co-contamination of several food products. Therefore, the present study investigated effect of single and combined exposures of aluminium and cadmium during pregnancy on cardio metabolic changes in mice. Following delivery and at the end of 78 days postnatal development, it was observed that exposure to Al and Cd during pregnancy altered indices of cardiac function via pathways related to angiotensin, cardiac troponin and oxidative stress signalling which may have impacted directly on the histoarchitectural features of the heart. Comparatively, prenatal exposure to Cd alone impacted more negatively to the heart in relation to exposure to either Al only or co-exposure to Al and Cd.

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Section: Resultssupporting

confidence: 93%