Purpose To explore the prevalence of symptoms of anxiety and depression, along with PTSD-and ED-related symptoms, across a sample of patients with Eating Disorders (EDs) compared to a group of healthy controls (HC) during the lockdown period in Italy; to assess whether patients' reported aforementioned psychiatric symptoms improved, remained stable or worsened with the easing of the lockdown measures. Methods t0 assessment (during lockdown): 59 ED patients and 43 HC completed an online survey, including the Depression, Anxiety and Stress Scale-21 items (DASS-21), the Impact of Event Scale-Revised (IES-R), the Perceived Stress Scale (PSS), and specific ad-hoc questions extracted from the Eating Disorder Examination-Questionnaire; t1 assessment (postlockdown): 40 EDs patients, a subset of the t0 sample, completed the same assessment 2 months after t0. Results EDs patients scored higher than HC at the DASS-21, IES-R and PSS. At t1, levels of stress, anxiety and depression were not different than at t0, but symptoms related to post-traumatic stress disorder (PTSD), patients' reported level of psychological wellbeing and specific EDs symptomatology improved. Discussion During the lockdown, EDs patients presented significantly higher levels of stress, anxiety, depression, PTSDand ED-related symptoms than HC. With the easing of the lockdown, PTSD-and ED-related symptoms improved, but high levels of stress, anxiety and depression persisted. Level of evidence Level I, experimental study.