“…The WHOQOL-BREF showed high internal consistency, and the fit of the hypothesized four domains of QOL was acceptable. In addition, the pattern of weak and strong standardized regression coefficients was consistent with previous research [13,20,21]. Weak standardized regression coefficients were found in reversed items (i.e., pain, medication, and negative feelings), while some domains seemed to make more important contributions to QOL (e.g., activities, work, self-esteem, spirituality) than others.…”