This paper discussed how the psychosociology of the physician
contributes to therapeutic and placebo effects. The mechanisms was
referred to as iatroplacebogenics, a term describing the study of placebo
effects produced by physicians.
Iatroplacebogenesis can be direct or indirect.
Direct iatroplacebogenesis includes:
1. Attitude to patients, which refers to the therapist’s interest,
warmth, friendliness, liking, sympathy, empathy, neutrality, disinterest,
hostility, and rejection. 2. Attitude to treatment, which refers to the therapist’s interest,
faith, belief, enthusiasm, conviction, commitment, optimism, positive
and negative expectations, skepticism, disbelief, and pessimism.
3. Attitude to results, which refers to data distortion caused by
random observer effects and by intentional and unintentional nonrandom
observer bias.
An extensive review of the literature demonstrates that these
attitudes of the physician are associated with therapeutic and placebo
effects. The explanation of how these factors influence results is less
clear, bift the following are suggested:
The primary and direct effect of the healer’s interest in the patient
is on reduction of guilt. It is also associated with increased potentials
for learning, conditioning, suggestibility, catharsis, and it stimulates
other factors which have been correlated with placebo effects. The
primary and direct effect of the therapist’s interest in treatment is the
mobilization of the patient’s hope and optimism.
This factor also has a direct effect on reduction of guilt.
The direct effect of interest in results is on nonrandom intentional
or nonintentional observer bias. Data are influenced, communicated,
distorted, and then used to confirm hypotheses.
All of these factors may now interact with the potential specific
effects of various therapies. Indirect iatroplacebogenesis is a subtle
mechanism that has not been considered in the literature.
The physician’s interest may be indirect, subtle, and paradoxical.
An interest in a theory and method of treatment, despite disinterest in
the patient, may produce placebo effects. This occurs when the patient
displaces the interest from the therapy to himself and experiences the
physician’s interest in his treatment as a personal one.
Thus, placebo effects are produced or augmented when the physician
is prestigious, dedicated to his theory and therapy, especially if it
is of his own innovation, or if he is a recent convert, and when the
therapies are elaborate, detailed, expensive, time-consuming, fashionable,
esoteric, and dangerous. Data in support of the concept of direct
and indirect iatroplacebogenesis were derived from the history of
medicine, psychopharmacology, case histories of patients treated with
psychochemotherapy and psychoanalysis, and many clinical and experimental
studies and observations about placebo and therapeutic effects.
The conclusion was reached that although the placebo effect is a
multideterminedphenomenon,iatroplacebogenesismay parsimoniously
help explain many observations about therapeut...