The quality coefficient as performance assessment parameter of straight line calibration curves in relationship with the number of calibration points

Beer, Jacques O. De; Naert, Caroline; Deconinck, Éric

doi:10.1007/s00769-011-0871-1

Cited by 14 publications

(10 citation statements)

References 17 publications

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“…Larger deviations present at larger concentrations tend to influence (weight) the regression line more than smaller deviations associated with smaller concentrations, and thus the accuracy in the lower end of the range is impaired. It is therefore very convenient [122][123][124] to analyse the plotted data and to make sure that they cover uniformly (approximately equally spaced) the entire range of signal response from the instrument (85). Data should be measured at random (to avoid confusing non-linearity with drift).…”

Section: Calibration Graphs: the Question Of Intercept Or Non-interceptmentioning

confidence: 99%

Fitting Models to Data: Residual Analysis, a Primer

Martín¹,

Adana²,

Asuero³

2017

Uncertainty Quantification and Model Calibration

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Section: Calibration Graphs: the Question Of Intercept Or Non-interceptmentioning

confidence: 99%

Fitting Models to Data: Residual Analysis, a Primer

Martín¹,

Adana²,

Asuero³

2017

Uncertainty Quantification and Model Calibration

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“…Table 2 summarizes for the twelve solvents the R² values and the quality coefficients. For all curves the g values were below 0.01 [21]. From this table it can clearly been concluded that the calibration curves for all components are linear within the chosen concentration ranges.…”

Section: Linearity Of the Calibration Linementioning

confidence: 73%

A validated GC–MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules

Deconinck

Canfyn

Sacré

et al. 2012

Journal of Pharmaceutical and Biomedical Analysis

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A fast headspace GC-MS method was developed and validated for the detection and quantification of residual solvents of all three ICH-classes in counterfeit tablets and capsules. The method was validated for 10 solvents, selected based on an initial screening of counterfeit medicinal products. The considered solvents were ethanol, 2-propanol, acetone, ethylacetate, chloroform, carbon tetrachloride, benzene, toluene, dichloromethane and ethylbenzene. The proposed method uses a Phenomenex 624 capillary column (60 m × 0.32 mm; 1.8 μm film thickness) (Phenomenex, Torrance, USA) with an oven temperature program from 60 °C (held for 5 min) to 270 °C at 25 °C/min. 270 °C is held for 10 min. The total run time is 23.4 min. The obtained method was fully validated by applying the "total error" profile. Calibration lines for all components were linear within the studied ranges. The relative bias and the relative standard deviations for all components were smaller than 5%, the β-expectation tolerance limits did not exceed the acceptance limits of ±10% and the relative expanded uncertainties were acceptable for all of the considered components. A method was obtained for the screening and quantification of residual solvents in counterfeit tablets and capsules, which will allow a fast screening of these products for the presence of residual solvents.

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“…De Beer et al 122 have presented new mathematical models which demonstrate the extent to which the number of calibration points defines the value of the quality coefficient for different values of 'g' (a parameter which controls the symmetry of the prediction interval of the abscissa value obtained from the confidence intervals around the curve). The result of this appeared to be that it was much harder to predict the quality of the calibration than is generally thought, and the authors provided an elaborated example of how to improve the quality of the calibration by lowering the g-value beneath a critical value.…”

Section: Chemometricsmentioning

confidence: 99%

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

Evans

Pisonero

Smith

et al. 2018

J. Anal. At. Spectrom.

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SUMMARY OF CONTENTS This review covers developments in 'Atomic Spectrometry'. It covers atomic emission, absorption, fluorescence and mass spectrometry, but excludes material on speciation and coupled techniques which is included in a separate review. It should be read in conjunctionwith the other related reviews in the series. [1][2][3][4][5][6] Sample introductionThis section covers developments in sample introduction for all instrumental methods. LiquidsLiquid sample introduction relates to methods wherein the sample is introduced into the instrument in the form of a liquid, such as through nebulization or into a thermal vaporizer; whereas in vapour generation the sample is initially in the form of a liquid but is converted to a vapour prior to introduction into the instrument. Sample pre-treatment.A general review of on-line preconcentration for ICP-MS has been published by Das et al. 7 , covering solid phase methods and including 63 references. Several reviews of sample pretreatment methods used for atomic spectrometry are worth noting because they focus on specific areas: Kocurova et al. 8and Jain and Verma 9 have reviewed advances in DLLME (53 references) and SDME (407 references) respectively; Zhao et al. the same authors studied the stability of the labelled complexes at different pH and temperature, and when subject to separation using LC. They reported a significant decrease in stability when LC separation was used, and some degradation at 37 °C compared to 2 °C.Li et al. An immunoassay-linked method using gold nano-particles has been developed by Jarujamrus et al. 33 . In this approach the monoclonal antibody-chloramphenicol was attached to a solid support. Antigen-chloramphenicol was labelled with gold nano-particles (10 nm) at pH 9.5, attached to a bovine serum albumin protein and mixed with unlabelled antigenchloramphenicol, which was then added to the antibody-chloramphenicol. for U and Th respectively in water samples.

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The quality coefficient as performance assessment parameter of straight line calibration curves in relationship with the number of calibration points

Cited by 14 publications

References 17 publications

Fitting Models to Data: Residual Analysis, a Primer

Fitting Models to Data: Residual Analysis, a Primer

A validated GC–MS method for the determination and quantification of residual solvents in counterfeit tablets and capsules

Atomic spectrometry update: review of advances in atomic spectrometry and related techniques

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