The quality of life among Sudanese Patients with Epilepsy, Khartoum, Sudan

Ibrahim, Etedal Ahmed A.; Ali, Lina Hussain Mustafa; Ahmed, Khabab Abbasher Hussien Mohamed; Omer, Mohammed Eltahier Abdalla

doi:10.21203/rs.3.rs-900915/v1

Cited by 2 publications

(2 citation statements)

References 34 publications

(42 reference statements)

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“…On the other hand, this study disagreed with other previous studies, which showed that the PT value was discovered to be significantly lesser in hypothyroid & hyperthyroid cases when compared with the control group [9,15].…”

Section: Discussioncontrasting

confidence: 99%

Evaluation Of serum p-selectin level In Patients with Thyroid Dysfunction..

Owis,

Mashahit,

El Shafy

et al. 2024

Fayoum University Medical Journal

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Introduction: Thyroid hormone has a significant impact on every cell in the body by altering the rate of growth, cellular progression and differentiation, and the change in the levels of micronutrients, hormone stages, protein synthesis, lipids, and CHO. The connection between thyroid problems and blood coagulation systems was first mentioned scientifically at the beginning of the previous century. In patients with thyroid dysfunction, numerous acquired coagulation-fibrinolytic system abnormalities were studied. These deviations can range from minor lab anomalies to serious medical hemostatic dysfunction. Aim of the study:To evaluate novel biomarkers as thrombosis predictors in thyroid dysfunction patients. Subjects and Methods:This case-control study included 60 participants as follows; 20 patients in Group A, who have hyperthyroidism, have elevated thyroid functions, Group B contains 20 patients with hypothyroidism who have decreased thyroid function, and Group C consists of 20 individuals with normal thyroid function (the euthyroid group). Methods included taking a complete medical history (including OCPS use), age, gender, smoking, history of cancer, thromboembolic events, bleeding disorders, and thorough clinical examination. For lab tests and measurements of the CBC, PT, PTT, PC, TSH, FT4, D-dimer, and p-selectin level. Results:The study groups did not differ significantly from one another regarding the PT-INR, PTT, and D-dimer levels, as well as the CBC components. Additionally, PTT and PLT count levels were significant predictors of pselectin levels. Conclusion:It can be concluded that there was no significant variance among study groups concerning CBC components, PT-INR, PTT, and D-dimer level.

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Section: Discussioncontrasting

confidence: 99%

Evaluation Of serum p-selectin level In Patients with Thyroid Dysfunction..

Owis,

Mashahit,

El Shafy

et al. 2024

Fayoum University Medical Journal

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“…MAP in humans in the Sudan has never been investigated, neither in diseases that have been linked to it earlier (CD or IBD) nor in other diseases, more likely due to the scarce information on these diseases [ 32 – 34 ]. However, because of the relatively high prevalence of MAP in cattle in Khartoum, Sudan [ 35 ] in addition to the close contact between humans and animals, we hypothesize that MAP prevalence in human is higher than expected.…”

Section: Introductionmentioning

confidence: 99%

Mycobacterium avium subsp. paratuberculosis and microbiome profile of patients in a referral gastrointestinal diseases centre in the Sudan

Elmagzoub

Idris²,

Isameldin³

et al. 2022

PLoS ONE

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Mycobacterium avium subsp. paratuberculosis (MAP) causes Johne’s disease in animals with zoonotic potential; it has been linked to many chronic diseases in humans, especially gastrointestinal diseases (GID). MAP has been extensively studied in Europe and America, but little reports were published from Africa. Sudan is a unique country with close contact between humans and livestock. Despite such interaction, the one health concept is neglected in dealing with cases of humans with GID. In this study, patients admitted to the reference GID hospital in the Sudan over a period of 8 months were screened for presence of MAP in their faeces or colonic biopsies. A total of 86 patients were recruited for this study, but only 67 were screened for MAP, as 19 did not provide the necessary samples for analysis. Both real-time PCR and culture were used to detect MAP in the collected samples and the microbial diversity in patients´ faecal samples was investigated using 16S rDNA nanopore sequencing. In total, 27 (40.3%) patients were MAP positive: they were 15 males and 12 females, of ages between 21 and 80 years. Logistic regression analysis revealed no statistical significance for all tested variables in MAP positive patients (occupation, gender, contact with animal, milk consumption, chronic disease, etc.). A unique microbiome profile of MAP-positive patients in comparison to MAP-negative was found. These findings suggest that a considerable proportion of the population could be MAP infected or carriers. Therefore, increase awareness at community level is urgently needed to decrease the risk of MAP at human/animal interface. This study represents the first report of MAP in humans in the Sudan; nevertheless, a better view of the situation of MAP in humans in the country requires a larger study including patients with other conditions.

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The quality of life among Sudanese Patients with Epilepsy, Khartoum, Sudan

Cited by 2 publications

References 34 publications

Evaluation Of serum p-selectin level In Patients with Thyroid Dysfunction..

Evaluation Of serum p-selectin level In Patients with Thyroid Dysfunction..

Mycobacterium avium subsp. paratuberculosis and microbiome profile of patients in a referral gastrointestinal diseases centre in the Sudan

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