The Quality of Life and Psychological, Social
and Cognitive Functioning of Patients with Acromegaly

Szczęśniak, Dorota; Jawiarczyk-Przybyłowska, Aleksandra; Rymaszewska, Joanna

doi:10.17219/acem/38156

Cited by 37 publications

(31 citation statements)

References 40 publications

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“…disease, the burden of comorbidities, and, potentially, the burden of therapy [3,4]. With references to the guidelines, not only biochemical parameters but also the improvement of the QoL should be considered in clinical practice as tools to assess the success in acromegaly treatment [6,7].…”

Section:  Prace Oryginalnementioning

confidence: 99%

Czy istnieje różnica w jakości życia i występowaniu objawów psychiatrycznych u chorych na akromegalię i inne choroby przewlekłe?

Szczęśniak

Jawiarczyk-Przybyłowska²,

Matusiak³

et al. 2015

Endokrynologia Polska

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Section:  Prace Oryginalnementioning

confidence: 99%

Czy istnieje różnica w jakości życia i występowaniu objawów psychiatrycznych u chorych na akromegalię i inne choroby przewlekłe?

Szczęśniak

Jawiarczyk-Przybyłowska²,

Matusiak³

et al. 2015

Endokrynologia Polska

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“…Half of the patients with acromegaly have anxiety and insomnia related to the acceptance of the illness. The psychological component seems therefore to play an important for patient Qol (7). Coping strategies, such as problem-solving and positive thinking actions, may diminish psychological distress such as anxiety and depression also in acromegalic patients.…”

Section: Discussionmentioning

confidence: 99%

“…These serious and at times irreversible changes have already occurred by the moment of diagnosis, predisposing the patient to affective disorders, commonly depression. There is also a tendency to sleep disorders, impaired attention, memory and social isolation (7,8). All these disease-related comorbidities can severely affect the quality of life of acromegaly patients and may lead to psychological sequelae (9)(10)(11)(12)(13)(14).…”

Section: Introductionmentioning

confidence: 99%

"The impact of biochemical control on the quality of life of patients with acromegaly"

Solomon¹,

Preda²,

Gavrilescu³

et al. 2019

BPI

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Purpose: Quality of life (Qol) is undoubtedly important for patient case management. The current goal of a treatment extends therefore beyond biochemical monitoring, including the physical, mental and social state of wellbeing. We aimed to correlate disease activity with the perception of Qol in acromegalic patients. Methods: We performed a single center cross-sectional study on 26 patients: 9 men (34.6%) and 17 women (65.4%), with a mean age of 53 ± 11.5 years. Eleven patients (42.3%) had a biochemically controlled disease, while 15 subjects (57.7%) had an active disease. Results: The mean total score of the quality of life was 60.9 ± 12.6 in women, ranging from 40 to 85, while for men, the mean total score was of 64.04 ± 14.78, ranging from 42 to 85 (p=0.575). There was no significant difference between the mean AcroQol scores of patients with controlled or active disease (62.54 ± 13.42 vs 61.23 ± 13.46, p = 0.804). Patients younger than 60 had a significantly lower total score compared to older patients, (58.36 ± 14.17 vs 64.26 ± 12.44, p=0.047). Rural residents also scored lower than patients belonging to the urban region: (58.18 ± 11.21 vs 67.19 ± 14.39, p=0.048). Disease duration was negatively correlated with total score on AcroQol (r =-0.253, p= 0.045). We did not find significant correlations between GH and IGF1 levels and AcroQol (p=0,622 and p = 0.844, respectively). Conclusions: We found no significant differences between males and females, as well as between patients with active and controlled disease regarding the Qol, but other factors like 72/Bulletin of Integrative Psychiatry New Series  December 2019  Year XXV  No. 4 (83) age or locality provenience may play some role for the perceived health status and quality of life in acromegalic patients

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“…QoL improvement in patients with acromegaly is an inherent element of effective treatment. Patients require coordinated, highly specialized and interdisciplinary care, including psychological treatment (31,32).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of factors affecting quality of life in acromegaly

Zgliczyński¹,

Woźniak²,

Zgliczyński³

2017

PNM

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Introduction. Acromegaly is a chronic, rare disease caused by excessive secretion of growth hormone, usually by a pituitary tumor. This disease causes multisystem complications, which lead to shortened life expectancy of patients and also affect their Quality of Life. Aim. Aim of the study was to evaluate factors influencing Quality of Life in acromegaly. Material and methods. The material consisted of 52 patients (29 women and 23 men) with acromegaly aging from 25 to 91 (average 50.6 years old). Quality of life was evaluated with the use of AcroQoL survey which contains three symptom scales: "Physical", "Appearance" and "Social relations". Statistical analysis was performed using SPSS software. Results. Average proclaimed duration of disease was 12.3 years, 43 patients had surgery, 6 underwent radiotherapy. Among declared complications, osteoarticular changes occurred in 32 (62%) patients, snoring 32 (62%), hypertension 24 (46%), diabetes 16 (31%), 8 (15%) suffered from cancer. Majority of people reported more than one disease complication. Most of respondents felt sick (63%). Frequency of physical ailments: tiredness (48%), weakness (40%), arthralgia (37%), 3/4 subjects were critical about their appearance. Conclusions. In the studied group: 1) factors with the greatest impact on the Quality of Life were: osteoarticular complications (pain), respiratory dysfunctions (snoring) and changed appearance; 2) no disease influence on social relations was found; 3) Quality of Life was not correlated with age of patients and duration of the disease; 4) pensioners reported significantly the largest number of Quality of Life restrictions in terms of physical symptoms, while working people had significantly better Quality of Life. S t r e s z c z e n i e Wstęp. Akromegalia jest to przewlekła, rzadka choroba spowodowana nadmiernym wydzielaniem hormonu wzrostu, najczęściej przez guz przysadki. Choroba prowadzi do powikłań wielonarządowych, czego wynikiem jest skrócenie średniej długości życia chorych oraz pogorszenie jego jakości. Cel pracy. Celem pracy była ocena czynników wpływających na jakość życia w akromegalii. Materiał i metody. Materiał stanowiło 52 chorych (29 kobiet i 23 mężczyzn) z akromegalią w wieku 25-91 lat (średnia 50,6 roku). Jakość życia oceniano przy użyciu formularza AcroQoL zawierającego trzy obszary objawów: "Objawy fizyczne", "Wygląd zewnętrzny" oraz "Relacje społeczne". Analizę statystyczną przeprowadzono przy użyciu programu SPSS. Wyniki. Średni czas trwania akromegalii szacowany przez pacjentów wynosił 12,3 roku, 43 chorych leczono operacyjnie, a 6 poddano radioterapii. Wśród deklarowanych powikłań choroby zmiany zwyrodnieniowe układu kostno-stawowego występowały u 32 (62%) osób, chrapanie u 32 (62%), nadciśnienie tętnicze u 24 (46%), cukrzyca u 16 (31%), a chorobę nowotworową przebyło 8 (15%) badanych. Większość osób zgłosiła obecność więcej niż jednego z ocenianych powikłań akromegalii. Większość ankietowanych (63%) czuło się osobą chorą, z dolegliwości fizycznych najczęściej zgłaszali: zmęczenie (...

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The Quality of Life and Psychological, Social and Cognitive Functioning of Patients with Acromegaly

Cited by 37 publications

References 40 publications

Czy istnieje różnica w jakości życia i występowaniu objawów psychiatrycznych u chorych na akromegalię i inne choroby przewlekłe?

Czy istnieje różnica w jakości życia i występowaniu objawów psychiatrycznych u chorych na akromegalię i inne choroby przewlekłe?

"The impact of biochemical control on the quality of life of patients with acromegaly"

Evaluation of factors affecting quality of life in acromegaly

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