The quantitative investigation of spark plasma on skin parameters: skin elasticity, thickness, density, and biometric characteristics

Abstract

Cold atmospheric plasma has been developed and utilized as a novel technique for skin rejuvenation because of its various effects on cells and living things. This study investigated the accuracy of this claim and any possible side effects of using spark plasma to rejuvenate skin. The present work is the first quantitative investigation using animal models. 12 Wistar rats were divided into two groups for this investigation. To compare the skin's natural process with the treated skin, the first group underwent a single session of plasma therapy, while the second group served as the control group. The back of the necks of the samples was shaved for 20 cm. Before beginning treatment, the MPA9 multifunctional skin tester was used to determine the melanin index, erythema index, and transepidermal water loss (TEWL). The skin's thickness and density were assessed using sonography, and its elasticity index was calculated using a Cutometer. The samples were exposed to plasma radiation in the designated area (in a triangular pattern). The signs mentioned above were examined immediately after the following therapy and at the weekly appointment, 2-4 weeks later. Optical spectroscopy was also used to demonstrate the presence of active species.

Comparing the efficacy of plasma exeresis and cryotherapy for the treatment of seborrheic keratosis: A randomized controlled trial

“…Despite the high temperature of this type of plasma, the controlled form creates microburn on the skin. The plasma exeresis medical devices ionize the atmospheric gas between the device and the skin, sublimate the surface layers, and uniformly heat it 9–11 …”

“…In a study done by Ghasemi et al., investigating the effect of plasma exeresis on skin parameters on rat models, it was concluded that plasma exeresis improves skin thickness, density, and elasticity, most likely due to increased keratinocytes and fibroblasts 9 . In one study conducted by Rossi et al., the efficacy of using plasma was evaluated in 250 patients with benign skin lesions (dermal nevi, fibroma, keratosis, xanthelasma), nonsurgical blepharoplasty, wrinkles (perioral, glabellar, neck, and preauricular regions), active acne, and scarring (postacneic and posttraumatic).…”

“…Plasma exeresis is a new minimally invasive technique that has recently gained attention in recent years. The plasma exeresis medical devices generate plasma energy by ionizing atmospheric gas between the device and the skin 9–11 . The resulting plasma exeresis sublimates the surface layers and transfers the stored heat energy to the skin surface.…”

“…The resulting plasma exeresis sublimates the surface layers and transfers the stored heat energy to the skin surface. Recent studies have shown the efficacy of this technology for the treatment of various dermatologic indications including perioral wrinkles, acne, and nonsurgical blepharoplasty 9,10,12,13 …”