The Quantitative Phytochemistry and Hypoglycaemic Properties of Crude Mesocarp Extract of Hyphaene thebaica (doumpalm) on Normoglycemic Wistar Albino Rats

Anti-Diabetic Potential of Hyphaene Thebaica Fruit in Streptozotocin-Induced Diabetic Rats

“…Shehu et al, (2014) observed a dose dependent reduction in fasting blood glucose of diabetic rats with a dose administration of 400 mg/dl methanol extract of H. thebaica fruit having the highest (28.4%) decrease which was almost 2 folds higher than that observed in glibenclamide treated group. The present study correlated with the reports by Auwal et al, (2012), Shehu et al, (2014), andBayad (2016).…”

“…Inhibition of glucosidase activity regulates blood sugar level by postponing sugar breakdown (Yin et al, 2014). Auwal et al, (2012) reported oral administration of aqueous mesocarp extract of H. thebaica experimentally caused a significant decrease in blood glucose level in wistar albino rats, at 12 to 18 h post administration. Shehu et al, (2014) observed a dose dependent reduction in fasting blood glucose of diabetic rats with a dose administration of 400 mg/dl methanol extract of H. thebaica fruit having the highest (28.4%) decrease which was almost 2 folds higher than that observed in glibenclamide treated group.…”

Traditional medicinal plants used for the treatment of diabetes in the Sudan: A review

“…In this paper, an effort was made to refer to the different parts of 38 plant species that are used in the Sudanese traditional medicine (Table 1). Interestingly, some of these plants have already been reported in previous studies originated from other countries like Algeria (Houacine et al, 2012), Iran (Mikaili et al, 2013), Egypt (Helal et al, 2014), India (Singh et al, 2015), Nigeria (Auwal et al, 2012) and Saudi Arabia (Bamosa, 2010). The reviewed plants have been evaluated, in in vivo experiments with diabetic animals that were induced either by alloxan or streptozotocin (Fröde and Medeiros, 2008) …”

“…Oral administration of aqueous extract of H. thebaica mesocarp experimentally caused a significant decrease in blood glucose level in Wistar albino rats, at 12 to 18 h post administration (Auwal et al, 2012). Aqueous extract improved glucose and insulin tolerance, and significantly lowered blood glycosylated hemoglobin levels.…”