The Radiologic Diagnosis of Autopsyproven Ventilator-associated Pneumonia

Wunderink, Richard G.; Woldenberg, Lee S.; Zeiss, Jacob; Day, Claudia M.; Ciemins, John; Lacher, David A.

doi:10.1378/chest.101.2.458

Cited by 291 publications

(48 citation statements)

References 10 publications

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“…Our prior investigation, 16 as well as previous reports by Wunderink 17 and Lefcoe 4 emphasizes the inaccuracy of the portable chest radiograph in patients requiring mechanical ventilatory support. Radiographic changes may lag behind the clinical manifestations of VAP and portable chest radiography does not permit adequate visualization of the posterior segments of the lung.…”

mentioning

confidence: 51%

Is Bilateral Protected Specimen Brush Sampling Necessary for the Accurate Diagnosis of Ventilator-Associated Pneumonia?

Butler¹,

Best²,

Oster³

et al. 2004

The Journal of Trauma: Injury, Infection, and Critical Care

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mentioning

confidence: 51%

Is Bilateral Protected Specimen Brush Sampling Necessary for the Accurate Diagnosis of Ventilator-Associated Pneumonia?

Butler¹,

Best²,

Oster³

et al. 2004

The Journal of Trauma: Injury, Infection, and Critical Care

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“…Additionally, Meduri et al [84] revealed that the fibroproliferative phase of ARDS was associated with many of the typical signs and symptoms of an infectious process, such as fever, leukocytosis, and radiographic infiltrates. Several autopsy studies have reported underdiagnosis and overdiagnosis of pneumonia in the setting of acute lung injury [85].…”

Section: Noninfectious Etiologies Of Nonresolving Pneumoniamentioning

confidence: 99%

Nonresolving Pneumonia

Weyers¹,

Leeper²

2005

Clinics in Chest Medicine

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Uncertainty over the expected clinical course of a community-acquired or nosocomial pneumonia is a common reason for pulmonary consultation. Determining which patients with prolonged pneumonia and at what point during therapy they should undergo further evaluation can be challenging. This article reviews "normal" resolution times for the most common pneumonias, risk factors for delayed resolution, and infectious and noninfectious conditions that can cause nonresolving pneumonia. An approach to the evaluation of the patient with this common problem is described.

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“…Acknowledged clinical indicators of pneumonia (pyrexia, purulent secretions, cough and a leucocytosis) are unreliable in critically ill, ventilated patients [44,46,48,49]. The diagnosis of pneumonia based on the evolution of signs on chest X-ray is similarly hampered by the lack of specificity of radiographic changes [50]. Though an appreciation of the sequence of radiographic changes seen in uncomplicated ARDS is theoretically useful in predicting superimposed pneumonic consolidation, in practice the diagnostic accuracy of chest radiography in these circumstances is low [51].…”

Section: A) Infectionmentioning

confidence: 99%