The Radiosurgical Treatment of Arteriovenous Malformations: Obliteration, Morbidities, and Performance Status

Linac Stereotactic Radiosurgery for the Treatment of Small Arteriovenous Malformations: Lower Doses Can Be Equally Effective

“…In this study, 73.7% of patients presented with hemorrhage before SRS, which may be associated with the fact that over 50% of our patients had AVMs in a deep location. The AVMs' cumulative probability of obliteration in five years was 82.47%, results that are similar to those reported by other series [8,21,22,[27][28][29][30][31][32][33][34][40][41][42] . Complete AVMs occlusion was higher compared with that reported by Skjoth-Rasmussen et al [42] , who reported 78% occlusion in small AVMs of less than 10 cm in volume.…”

“…The annual hemorrhage risk was not determined, considering our low re-hemorrhage rate. Sun et al [41] illustrated, in two cases, that AVM size is not necessarily predictive of hemorrhage risk and that hemorrhage may still occur after angiographic AVM obliteration. This phenomenon has also been observed in other studies that report an elevated risk of hemorrhage in incompletely obliterated lesions [32,62,63] .…”

Cerebral Arteriovenous Malformations and Epilepsy, Part 1: Predictors of Seizure Presentation

“…However, AVM-associated epilepsy may also be debilitating and adversely impact a patient's quality of life (24). Seizures are the most common presentation of unruptured AVMs and are the second most frequent presentation for all AVM patients following hemorrhage (19,34,45).…”

Cerebral Arteriovenous Malformations and Epilepsy, Part 2: Predictors of Seizure Outcomes Following Radiosurgery

“…Seizures are the second most common clinical manifestation of cerebral arteriovenous malformations (AVM) following hemorrhage and are the most common presentation of patients with unruptured AVMs (18,42,45,57,59).…”