The Rapidly Changing Landscape of Multiple Sclerosis Immunomodulatory Therapy: A Retrospective Chart Review in the United Arab Emirates

Schiess, Nicoline; Holroyd, Kathryn Brown; Aziz, Faisal Aziz Abdul; Huether, Katherine; Szólics, Miklós; Alsaadi, Taoufik

doi:10.4172/2376-0389.1000203

Cited by 4 publications

(1 citation statement)

References 32 publications

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“…Rates of depression in the Emirate of Abu Dhabi have ranged from 22% in undergraduate students attending Al Ain University of Science and Technology 20 to 13.9% in a random sampling of 1224 households in Abu Dhabi. 21 Anxiety was cations, 24 it will be interesting to note whether the rates of depression in this population change.…”

Section: Discussionmentioning

confidence: 99%

Multiple Sclerosis, Anxiety, and Depression in the United Arab Emirates

Schiess¹,

Huether²,

Holroyd³

et al. 2019

International Journal of MS Care

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Background: Depression rates in the multiple sclerosis (MS) population in the Arab world have rarely been reported despite people with MS generally having higher rates of depression. We examined depression rates in 416 people with MS versus the general population of Abu Dhabi, United Arab Emirates, and their treatment. Methods: A retrospective medical record review of 416 people with MS (age range, 16–80 years) followed up at four large government hospitals in Abu Dhabi was conducted to determine the percentage of people with MS diagnosed as having depression or anxiety. Results: The depression rate in people with MS (10.8%) was close to that in the general population of Abu Dhabi. The adjusted odds ratios of depression by selected variables showed that there was a significant difference (P = .003) between females and males in reporting depression, with more females reporting depression than males. Greater MS duration was also associated with a higher likelihood of being depressed (P = .025). The anxiety rate in the cohort (4.8%) was lower than that in the general Abu Dhabi population (18.7%). Conclusions: The depression rate in people with MS in Abu Dhabi was close to that of the general Abu Dhabi population, but the anxiety rate in people with MS was lower. Explanations for these low rates include possible underreporting by patients and physician factors such as time limitations in busy clinics. Cultural aspects such as strong family support systems and religious factors in this predominantly Muslim population are also possible factors that warrant further investigation.

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Section: Discussionmentioning

confidence: 99%

Multiple Sclerosis, Anxiety, and Depression in the United Arab Emirates

Schiess¹,

Huether²,

Holroyd³

et al. 2019

International Journal of MS Care

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Short term real-world Fingolimod efficacy and safety in Emirati patients with multiple sclerosis

Ceccarelli

Mifsud

Abusamra

et al. 2020

Journal of Clinical Neuroscience

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Neuroprotective Role of Medicinal Plants from North Eastern Region of India

Bhattacharjee

Deka

Shivavedi

et al. 2023

Traditional Medicine for Neuronal Health

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The term neurodegenerative disease means the loss of neuronal cells in the brain, including Alzheimer's disease, Parkinson's disease, Multiple sclerosis, and Huntington's disease. It is one of the most common types of disease associated with elevated rates of mortality and morbidity worldwide. At the same time, modern allopathic medicines have a large number of synthetic chemicals for the symptomatic treatment and control of these diseases. These drugs have failed miserably due to clinical insufficiency and debilitating adverse effects. In the past decade, natural ingredients have gained notable interest in the prevention and treatment of neurodegeneration due to their powerful anti-inflammatory and anti-oxidant properties with minimal side effects. However, there is also an issue of safety and effectiveness due to the absence of an ample amount of research findings. The most common cellular mechanism for every neurodegenerative disorder is neuroinflammation and oxidative stress. Several preclinical and clinical studies conducted across the world have demonstrated that different bioactive compounds of herbal origin can potentially arrest these processes to prevent or treat neurodegeneration and can be developed into promising pharmaceutical formulations. This article discusses and analyses the various herbal compounds, such as Allium sativum, Camella sinensis, Centella asiatica, Coriandrum sativum, Crocus sativus, Glycyrrhiza glabra, and Morus alba used for phytotherapy of neurodegenerative diseases by combining recent in vitro and in vivo models.

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The Rapidly Changing Landscape of Multiple Sclerosis Immunomodulatory Therapy: A Retrospective Chart Review in the United Arab Emirates

Cited by 4 publications

References 32 publications

Multiple Sclerosis, Anxiety, and Depression in the United Arab Emirates

Multiple Sclerosis, Anxiety, and Depression in the United Arab Emirates

Short term real-world Fingolimod efficacy and safety in Emirati patients with multiple sclerosis

Neuroprotective Role of Medicinal Plants from North Eastern Region of India

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