The Rare Togetherness of Bladder Leiomyoma and Neurofibromatosis

Yücel, Cem; Budak, Salih; Kısa, Erdem; Çelik, Orçun; Kozacıoğlu, Zafer

doi:10.1155/2018/2302918

Cited by 3 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several endocrine alterations and genomic mutations have been associated with an increased risk of bladder leiomyoma [10,11]; however, our patient did not screen positive for any of them.…”

Section: Discussioncontrasting

confidence: 75%

Incidental Urinary Bladder Leiomyoma: A Successful Long Term Conservative Treatment Based on Pre-operatory Magnetic Resonance Imaging Findingsr

Prayer-Galetti¹,

Scagliori²,

Stramare³

et al. 2018

J Cancer Res Oncobiol

View full text Add to dashboard Cite

Background: Leiomyomas are benign mesenchymal neoplasms which rarely occur in the urinary bladder, accounting for just 0.43% of all bladder tumours. Due to the paucity of data, very little is known about diagnosis, treatment and follow-up. Thus, despite their nonmalignant nature, they may be considered a true therapeutic challenge. Objective: Conservative management is paramount when assessing and managing benign neoplasms. It is the responsibility of the surgeon to tailor the most appropriate surgery for each patient, finding the best balance between oncologic and functional outcomes and future quality of life. Case report: We present a case report of a patient who was incidentally diagnosed with a large, asymptomatic intramural leiomyoma of the urinary bladder. Following abdominal imaging, biopsy specimens were obtained through cystoscopy, and a transurethral resection of the bladder (TURB) was eventually performed. Imaging findings including Ultrasonography (US), triple-phase Computed Tomography Urography (CTU) and Magnetic Resonance Urography (MRU) are reported, and the most representative images are shown. The patient has been successfully managed with staged TURB and then close outpatient follow-up, and she is currently recurrence-free 8 years after the last endoscopic treatment. Conclusion: Despite the benign nature of leiomyomas, the surgical options for these tumours range from TURB to radical cystectomy. Here, we underline how a conservative approach may be successful regardless of the size and site of the lesion, thus preserving the bladder and the patient's quality of life without affecting the oncologic outcomes.

show abstract

“…Several endocrine alterations and genomic mutations have been associated with an increased risk of bladder leiomyoma [10,11]; however, our patient did not screen positive for any of them.…”

Section: Discussioncontrasting

confidence: 75%

Incidental Urinary Bladder Leiomyoma: A Successful Long Term Conservative Treatment Based on Pre-operatory Magnetic Resonance Imaging Findingsr

Prayer-Galetti¹,

Scagliori²,

Stramare³

et al. 2018

J Cancer Res Oncobiol

View full text Add to dashboard Cite

show abstract

“…As recent studies have shown promise in establishing best practices for evaluation and management, we reviewed the related studies on the last five years between 2016 and 2021. To review the features of bladder leiomyoma such as symptoms, diagnosis tools, treatment and prognosis, a literature search of PubMed and the Web of Science was conducted, which included 22 cases of bladder leiomyomas in 17 publications as shown in Table 1 (1,(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18). The symptoms vary according to the location of the tumor, and may even be asymptomatic (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Giant Sized Extravesical Bladder Leiomyoma Mimicking Uterine Cervical Leiomyoma: A Case Report With 8 Years’ Postoperative Follow-Up and a Review of the Literature

Tosun¹,

Sözen²,

Tefik³

et al. 2021

jmed

View full text Add to dashboard Cite

The incidence of bladder leiomyoma is estimated at only 0.43% because most bladder tumors arise from the urothelium. Moreover, 30% of them are the extra-vesical type. The symptoms include urinary tract obstruction, bladder irritation, and dysuria, with the possibility of dyspareunia or hematuria depending on the size and location of the tumor. Bladder leiomyomas cannot be diagnosed solely by combining symptoms and imaging techniques. We present a rare case of giant sized extravesical-type bladder leiomyoma with a diameter of 15.5x14.5x14 cm, which was misdiagnosed as a uterine cervical leiomyoma. It caused unilateral ureteral distension without related symptoms. During the 8-year postoperative follow-up, the patient had two healthy full-term pregnancies and no recurrence was observed. We reviewed the literature of the most recent five years and discussed the characteristics of 22 bladder leiomyoma cases. Unlike the literature, the present case is unique due to the giant size of the bladder leiomyoma, its ureteral complications, and long follow-up period. Bladder leiomyomas are rare bladder tumors which should be borne in mind during the differential diagnosis of a pelvic mass. Surgical excision is the most useful procedure for diagnosis and treatment.

show abstract

Case series – Prioritizing bladder-sparing treatments in patients with urinary tract leiomyoma: A report of three cases and updated literature review

McNall

Park²,

Gopal³

et al. 2022

CUAJ

View full text Add to dashboard Cite

Urinary tract leiomyomas are rare, benign mesenchymal tumors that are traditionally treated with complete surgical excision. We present three cases of urinary tract leiomyoma — two located in the bladder and one in the ureter. Both bladder leiomyomas were treated with transurethral resection of bladder tumor (TURBT) with no evidence of recurrent disease, while the upper tract leiomyoma was managed with surveillance by patient preference, which to our knowledge, has not been previously described. The ureteral leiomyoma has remained stable at five years followup from initial diagnosis. Given the benign nature of leiomyomas and the overall low recurrence rate reported in the literature, bladder-sparing options should be emphasized when feasible, with active surveillance potentially applicable for highly select patients.

show abstract

The Rare Togetherness of Bladder Leiomyoma and Neurofibromatosis

Cited by 3 publications

References 8 publications

Incidental Urinary Bladder Leiomyoma: A Successful Long Term Conservative Treatment Based on Pre-operatory Magnetic Resonance Imaging Findingsr

Incidental Urinary Bladder Leiomyoma: A Successful Long Term Conservative Treatment Based on Pre-operatory Magnetic Resonance Imaging Findingsr

Giant Sized Extravesical Bladder Leiomyoma Mimicking Uterine Cervical Leiomyoma: A Case Report With 8 Years’ Postoperative Follow-Up and a Review of the Literature

Case series – Prioritizing bladder-sparing treatments in patients with urinary tract leiomyoma: A report of three cases and updated literature review

Contact Info

Product

Resources

About