2004
DOI: 10.1016/j.physbeh.2004.02.010
|View full text |Cite
|
Sign up to set email alerts
|

The rat exposure test: a model of mouse defensive behaviors

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

6
73
1
13

Year Published

2004
2004
2024
2024

Publication Types

Select...
5
3
1

Relationship

0
9

Authors

Journals

citations
Cited by 116 publications
(93 citation statements)
references
References 44 publications
6
73
1
13
Order By: Relevance
“…A possible explanation for these discrepancies may be the different genetic background of the mice used in the two studies: Linden used the CD1 mouse strain, whereas for our study, we used mice backcrossed into the C57Bl/6 background. These two mouse strains show important behavioral differences in stress-and anxiety-related tests, such as predator-induced freezing and risk assessment and exploration in the light dark box (e.g., Yang et al 2004;Kinsey et al 2007), which may produce also differential neuronal activation upon exposure to stress and/or drugs. Indeed, a recent experiment carried out in our lab showed strain-dependent differential neuronal activation in response to stress, e.g., by exposure to aversive stimuli (Hetzenauer and Singewald, unpublished).…”
Section: Ly341495-induced C-fos Expression In Wt Micementioning
confidence: 99%
“…A possible explanation for these discrepancies may be the different genetic background of the mice used in the two studies: Linden used the CD1 mouse strain, whereas for our study, we used mice backcrossed into the C57Bl/6 background. These two mouse strains show important behavioral differences in stress-and anxiety-related tests, such as predator-induced freezing and risk assessment and exploration in the light dark box (e.g., Yang et al 2004;Kinsey et al 2007), which may produce also differential neuronal activation upon exposure to stress and/or drugs. Indeed, a recent experiment carried out in our lab showed strain-dependent differential neuronal activation in response to stress, e.g., by exposure to aversive stimuli (Hetzenauer and Singewald, unpublished).…”
Section: Ly341495-induced C-fos Expression In Wt Micementioning
confidence: 99%
“…2) was developed and validated by Yang and coworkers [49] to facilitate measurement of risk assessment behaviors in mice. Testing procedures were conducted in a 46 × 24 × 21 cm clear polycarbonate cage (exposure chamber) covered with a metal lid.…”
Section: Ret Apparatus-mentioning
confidence: 99%
“…These results, pointing to alterations in locomotor activity [25], reflects a reduced motivation to explore as a consequence of increased anxiety. SAP behaviour in the elevated plus maze has been related to risk assessment and defensive behaviours [26,27]. Since it has also been shown to be particularly responsive to various anxiolytic drugs, high levels of this response have been considered a reliable index of increased anxiety [25,28,29].…”
Section: Discussionmentioning
confidence: 99%