The Rate of Absorption of Synthetic Lysine and Dietary Protein in the Upper Half of the Small Intestine of Pigs

Abstract

The aim of the present work was to estimate the rate of lysine absorption in the upper part of the small intestine as related to the absorption of total nitrogen and other amino acids in pigs given feed (barley + sesame meal) supplemented with lysine and fed once or 4 times daily. The experiments were carried out on 6 pigs fitted with reentrant cannulas sited in 3 of them about 4 m and in an other 3 about 9 m distal to the pylorus (mean intestine length was about 18 m). The frequency of feeding influenced the rate of flow of total nitrogen and lysine through the intestine. The content of lysine in the digesta (g/16 g N) during the first 5 hours after morning feeding, and particularly between 8.00-10.00 h, was much higher with once daily than with four times daily feeding while during the subsequent 15 hours the reverse was true. The absorption of lysine occurred at a faster rate than that of the other amino acids and was closest to that of arginine and methionine. On the whole, the net absorption rate of essential amino acids in the upper part of the intestine of pigs was as follows: Lys, Met greater than His, Phe, Leu greater than Trp, Ile, Val greater than Thr (Cys). It seems that the more uniform passage through and absorption from the alimentary tract of synethetic lysine and dietary protein, observed at frequent feeding could contribute to their better utilization for protein synthesis in the organism.

Threonine Requirement for Reproduction in Swine

“…Although Longenecker and Hause (1958) had reported that supplemental free amino acids and protein-derived amino acids enter the circulatory system simultaneously, the discovery of rapid peptide trans port (Newey and Smyth, 1960) caused many researchers to question the efficiency of amino acid supplementation. However, Buraczewska et al (1978) substantiated the work of Longenecker and Hause by showing that, although peptide transport proceeds at a faster rate than amino acid transport, supplemental amino acids spend much less time in the stomach and, hence, reach the site of absorption sooner than peptides.…”

Industrial amino acids in diets for piglets and growing pigs

“…Results from several trials, however, imply lower values for added amino acids than for protein-bound ones (Eggum et al, 1985 a; Jorgensen and Fernandez, 1987). Increasing the frequency of feeding from one to two or more times per day improved availability of added amino acids (Batterham, 1974;Batterham and O'Neill, 1978;Partridge et al, 1985;Buraczewska and Buraczewski, 1980). Leibholz et al (1985) 98-99 % for M C-L-methionine.…”

Einfluß von Aminosäuren‐Zulagen auf die Futteraufnahme und die Proteinverwertung von Ferkeln

“…Es ist anzunehmen, dai3 nicht tierspezifische, sondern rationsabhangige Faktoren fur diesen Kurvenverlauf zwischen Lysinaufnahme und N-Retention verantwortlich sind. Maisproteine weisen bekanntlich einen hohen Leucinuber-schuB auf, der in diesen Untersuchungen die Wirkung der Lysinzulagen eingeschrankt haben kann.Moglicherweise werden aber auch synthetische Aminosauren rascher absorbiert als irn Proteinverband vorliegende Arninosauren(BURACZEWSKA et al 1980). Die Folge ware eine asynchrone Bereitstellung von Aminosauren am Ort der Proteinsynthese und eine geringe Ausnutzung bzw.…”