The rate of oocytes with granular cytoplasm is higher in women with endometrioma in ICSI cycles

Bilgiç, Bülent Emre; Eken, Meryem; Ayla, Şule; Köse, Ayşe Merve; Kutlu, Tayfun; İlhan, Gülşah

doi:10.1080/01443615.2021.1916803

Cited by 1 publication

(2 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3 According to another research that aimed to study the impact of endometrioma cysts on the morphology of oocytes and the fertility outcomes in ICSI cycles, although M II oocytes were fewer in patients with endometrioma, there was no significant statistical difference between the fertility rates of the two groups. 30 Contrary to the findings of the present research, based on one study that aimed to compare the IVF outcomes in women with and without endometriosis who have decreased ovarian reserves, endometrioma has no influence on the number of retrieved oocytes and the IVF outcomes such as implantation and the rate of live birth. 31 To interpret the above-mentioned contradictory findings, it should be noted that endometriosis is an estrogen-dependent chronic inflammatory disease and its pathogenesis is multifactorial in causing infertility.…”

Section: Discussioncontrasting

confidence: 86%

“…In line with the results of the present study regarding the mean number of M II oocytes, the fertilization rate, and embryo quality, based on a meta‐analysis study, although endometrioma was associated with a decrease in the number of M II oocytes retrieved in IVF/ICSI cycles, it had no negative influence on the total number of embryos and also on the number of high‐quality embryos 3 . According to another research that aimed to study the impact of endometrioma cysts on the morphology of oocytes and the fertility outcomes in ICSI cycles, although M II oocytes were fewer in patients with endometrioma, there was no significant statistical difference between the fertility rates of the two groups 30 . Contrary to the findings of the present research, based on one study that aimed to compare the IVF outcomes in women with and without endometriosis who have decreased ovarian reserves, endometrioma has no influence on the number of retrieved oocytes and the IVF outcomes such as implantation and the rate of live birth 31 …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Association between follicular fluid bacteria with inflammatory markers of the complete blood count and the outcomes of assisted reproductive technology in women with endometriosis: A case–control study

Kabodmehri,

Sharami,

Tavakoli

et al. 2024

Health Science Reports

View full text Add to dashboard Cite

Background and AimsEndometriosis is a common reason for infertility and poor outcomes of assisted reproductive technology (ART). Inflammation is involved in the pathogenesis of this disease. The presence of microorganisms in women with endometriosis may increase levels of inflammatory markers. The purpose of this study is to determine the relationship between the presence of bacteria in the follicular fluid with the inflammatory markers of the complete blood count (CBC) and the outcomes of in vitro fertilization (IVF) in women with endometriosis.MethodsThis case–control study was conducted on 74 patients undergoing IVF, referred to Al‐Zahra Hospital in Rasht (Iran) in 2021. The patients were divided into two case groups including 37 women with endometrioma and the control group, including 37 infertile women with a male factor and normal ultrasound. In total, 74 follicular fluids were collected from the case and control groups and were cultured in the laboratory. The relationship between culture results with IVF outcomes and the levels of CBC inflammatory markers including the number of white blood cells (WBCs), lymphocytes, neutrophils, neutrophil‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte ratio (LMR), and platelet‐to‐lymphocyte ratio (PLR), erythrocyte sedimentation rate (ESR), and c‐reactive protein (CRP) was analyzed.ResultsThere was no significant statistical difference between the frequency of bacteria present in the follicular fluid (p = 0.861), the mean rate of fertilization (p = 0.363), the frequency of CRP (p = 0.999), and the mean WBCs, lymphocytes, neutrophils, NLR, LMR, and PLR in the two groups. There was a significant statistical difference between the mean number of oocytes of metaphase II (p = 0.034) and the mean ESR (p = 0.018) in the two groups.ConclusionsIt seems necessary to evaluate follicular fluid as a biological substance that is considered an optimal factor for predicting oocyte quality, fertilization rate, embryo quality, and the success rate of ART.

show abstract

Section: Discussioncontrasting

confidence: 86%