The Ratio of the Blood Urea Nitrogen/Creatinine Index in Patients with Acute Renal Failure is Decreased due to Dextran or Mannitol

Abstract

Acute renal failure (ARF)

High-fat western diet-consumption alters crystalline silica-induced serum adipokines, inflammatory cytokines and arterial blood flow in the F344 rat

“…A comprehensive blood panel was used to detect changes in liver, kidney, and pancreatic function. Blood urea nitrogen (BUN) is a waste product produced by the liver and filtered by the kidneys; reduced BUN level is an indicator of reduced liver function [ 34 ]. Silica (STD + SIL) had no effect on BUN level ( Fig.…”

“…6 A), but BUN was reduced by HFWD-consumption at 8 wk. Creatine (CREA), a product of muscle mass homeostasis, is filtered by the kidneys and serum concentrations typically do not fluctuate; increased CREA level is an indicator of reduced kidney filtration [ 34 ]. Silica had no effect on CREA ( Fig.…”

Decreased Level of Albumin in Peripheral Blood Mononuclear Cells of Streptozotocin-Induced Diabetic Rats

“…Thereby, when BUN/CRE ratio was calculated with each individual rat, the ratio was on average 138.7 and this value was approximately 2-fold higher than that of normal rats (~65.6). The BUN/CRE ratio is considered to be a useful index to evaluate renal insufficiency [10]. It has also been suggested that acute renal insufficiency, which is developed in STZ-induced DM, causes an increase in the BUN/CRE ratio [20].…”

Selenium supplementation restores the decreased albumin level of peripheral blood mononuclear cells in streptozotocin-induced diabetic mice

“…Se supplementation decreased the elevated levels of TG, GLU and BUN/CRE ratio of STZ-mice. The BUN/CRE ratio is considered a useful index to evaluate renal insufficiency [ 8 ]. It has also been suggested that acute renal insufficiency, which is developed in STZ-induced DM, causes an increase in the BUN/CRE ratio [ 20 ].…”