The ratiometric fluorescent detection of anthrax spore biomarker based on functionalized silicon nanodots

Xu, Lan; Zhang, Yanan; Ji, Xinghu; He, Zhibing

doi:10.1007/s11696-019-00733-w

Cited by 6 publications

(4 citation statements)

References 31 publications

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“…The detection limit was about 24 nM, four orders of magnitude lower than the spores' infectious dosage (6 × 10 −5 M required). 135…”

Section: Applications Of Dye-functionalized Siqdsmentioning

confidence: 99%

“…The detection limit was about 24 nM, four orders of magnitude lower than the spores' infectious dosage (6 Â 10 À5 M required). 135 Zhou et al (2021) 136 conducted a synthesis on acetic functionalized SiQDs to detect the imbalance of Zn 2+ /Cd 2+ The imbalance reaction might lead to many severe diseases because antibiotics are deposited in animal products. Developing a functional material for detecting is challenging and attractive.…”

Section: In Biosensorsmentioning

confidence: 99%

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Silicon quantum dots: surface matter, what next?

Beri

2023

Mater. Adv.

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“…The detection limit was about 24 nM, four orders of magnitude lower than the spores' infectious dosage (6 × 10 −5 M required). 135…”

Section: Applications Of Dye-functionalized Siqdsmentioning

confidence: 99%

Section: In Biosensorsmentioning

confidence: 99%

Silicon quantum dots: surface matter, what next?

Beri

2023

Mater. Adv.

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“…Attributed to the elegant work of the direct preparation of water-soluble SiQDs, various kinds of SiQD-based photoluminescent biosensors have been elaborately developed. The target analytes include lactate dehydrogenase, hydrogen ion, glucose, heavy metal ions, DNA, thiols, cancer cells and bacteria [ 41 , 42 , 43 , 67 , 68 , 69 , 70 , 71 , 72 ]. The sensing mechanisms of the SiQD-based biosensors for the analytes are based on metal-enhanced fluorescence (MEF) [ 46 ], inner filter effect (IFE) [ 68 ], fluorescence resonance energy transfer (FRET) [ 73 ], surface energy transfer (SET) [ 74 ] and so forth.…”

Section: Design and Fabrication Of Siqd-based Photoluminescent Biosen...mentioning

confidence: 99%

Recent Advances in Silicon Quantum Dot-Based Fluorescent Biosensors

2023

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With the development of nanotechnology, fluorescent silicon nanomaterials have been synthesized and applied in various areas. Among them, silicon quantum dots (SiQDs) are a new class of zero-dimensional nanomaterials with outstanding optical properties, benign biocompatibility, and ultra-small size. In recent years, SiQDs have been gradually utilized for constructing high-performance fluorescent sensors for chemical or biological analytes. Herein, we focus on reviewing recent advances in SiQD-based fluorescent biosensors from a broad perspective and discussing possible future trends. First, the representative progress for synthesizing water-soluble SiQDs in the past decade is systematically summarized. Then, the latest achievement of the design and fabrication of SiQD-based fluorescent biosensors is introduced, with a particular focus on analyte-induced photoluminescence (fluorescence) changes, hybrids of SiQDs with other materials or molecules, and biological ligand-modification methods. Finally, the current challenges and prospects of this field are highlighted.

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“…Our group demonstrated that water-soluble SiNDs can be easily prepared at gram scale by the hydrothermal method [ 20 , 49 ]. Then a series of SiNDs-based ratiometric biosensors were constructed for sensing pH, mucin 1, Hg 2+ , DNA, and dipicolinic acid in human serums or the cellular environment [ 20 , 21 , 22 , 23 , 50 , 51 ]. For example, we developed a ratiometric fluorescent Hg 2+ sensor by covalent modification of SiND with Hg 2+ -specific 6-carboxyX-rhodamine (Rox)-tagged DNA ( Figure 3 A).…”

Section: Nanomaterial-based Ratiometric Fluorescent Biosensorsmentioning

confidence: 99%

Nanomaterial-Based Dual-Emission Ratiometric Fluorescent Sensors for Biosensing and Cell Imaging

et al. 2021

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Owing to the unique optophysical properties of nanomaterials and their self-calibration characteristics, nanomaterial-based (e.g., polymer dots (Pdots) quantum dots (QDs), silicon nanorods (SiNRs), and gold nanoparticle (AuNPs), etc.) ratiometric fluorescent sensors play an essential role in numerous biosensing and cell imaging applications. The dual-emission ratiometric fluorescence technique has the function of effective internal referencing, thereby avoiding the influence of various analyte-independent confounding factors. The sensitivity and precision of the detection can therefore be greatly improved. In this review, the recent progress in nanomaterial-based dual-emission ratiometric fluorescent biosensors is systematically summarized. First, we introduce two general design approaches for dual-emission ratiometric fluorescent sensors, involving ratiometric fluorescence with changes of one response signal and two reversible signals. Then, some recent typical examples of nanomaterial-based dual-emission ratiometric fluorescent biosensors are illustrated in detail. Finally, probable challenges and future outlooks for dual-emission ratiometric fluorescent nanosensors for biosensing and cell imaging are rationally discussed.

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The ratiometric fluorescent detection of anthrax spore biomarker based on functionalized silicon nanodots

Cited by 6 publications

References 31 publications

Silicon quantum dots: surface matter, what next?

Silicon quantum dots: surface matter, what next?

Recent Advances in Silicon Quantum Dot-Based Fluorescent Biosensors

Nanomaterial-Based Dual-Emission Ratiometric Fluorescent Sensors for Biosensing and Cell Imaging

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